QuickView for RPLp0 (gene)

Gene Symbol:

RPLP0 Homo sapiens

Full name:

ribosomal protein lateral stalk subunit P0

Synonyms:

L10E, LP0, P0, PRLP0, RPP0, 60S acidic ribosomal protein P0, 60S ribosomal protein L10E, acidic ribosomal phosphoprotein P0, large ribosomal subunit protein uL10, neutral ribosomal phosphoprotein P0, ribosomal protein, large, P0

Genomic Location:

Chr 12: 119118886-119123397

Description:

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of...

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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Gallus gallus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AGCYRWTTC_UNKNOWN ,  MEIS1BHOXA9_01 ,  TATAAA_TATA_01 ,  NKX62_Q2 ,  BACH2_01 ,  OCT1_03 ,  CTTTAAR_UNKNOWN ,  AAAYRNCTG_UNKNOWN ,  CCANNAGRKGGC_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  CEBPGAMMA_Q6

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Cytogenetic Map:

12q24.23

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