Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for RPS6KA6;jsessionid=E7B5DB9477979439F1C8BE0276B24088 (gene)


Gene Symbol:
RPS6KA6 Homo sapiens Homo sapiens
Full name:
ribosomal protein S6 kinase A6
Synonyms:
PP90RSK4, RSK-4, RSK4, S6K-alpha-6, p90RSK6, ribosomal protein S6 kinase alpha-6, 90 kDa ribosomal protein S6 kinase 6, S6K-alpha 6, p90-RSK 6, ribosomal S6 kinase 4, ribosomal protein S6 kinase, 90kDa, polypeptide 6
Genomic Location:
Chr X: 83205640-84362350
Description:
This gene encodes a member of ribosomal S6 kinase family, serine-threonine protein kinases which are regulated by growth factors. The encoded protein may be distinct from other members of this family, however, as studies suggest it is not growth factor dependent and may not participate in the same signaling pathways.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr X
Xq21.1





GO Molecular Function

cation binding | magnesium ion binding | ribonucleotide binding | ribosomal protein S6 kinase activity | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

regulation of ERK1 and ERK2 cascade | negative regulation of phosphorylation | negative regulation of MAPK cascade | negative regulation of embryonic development | intracellular signal transduction | negative regulation of cellular process | negative regulation of mesoderm development | nervous system development | negative regulation of protein phosphorylation | cellular process | negative regulation of signaling | regulation of embryonic development | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | ribosomal protein S6 kinase activity | response to stimulus | response to stress | protein serine/threonine kinase activity | negative regulation of metabolic process | protein modification process | macromolecule modification | negative regulation of ERK1 and ERK2 cascade | system development | nitrogen compound metabolic process | regulation of signal transduction | DNA damage response, signal transduction by p53 class mediator | negative regulation of phosphate metabolic process | multicellular organism development | regulation of MAPK cascade | phosphorus metabolic process | cellular response to DNA damage stimulus | regulation of phosphorylation | DNA damage response, signal transduction resulting in transcription | signal transduction in response to DNA damage | cellular response to stress | regulation of nitrogen compound metabolic process | regulation of cellular protein metabolic process | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | regulation of protein phosphorylation | regulation of mesoderm development | protein metabolic process | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | anatomical structure development | metabolic process | protein kinase activity | organic substance metabolic process | negative regulation of cellular protein metabolic process | regulation of phosphate metabolic process | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of signal transduction | signaling | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | cellular protein metabolic process | regulation of developmental process | kinase activity | developmental process | cellular protein modification process | central nervous system development | cellular metabolic process | signal transduction by p53 class mediator | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | fibrillar center | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | nucleoplasm | mitochondrion | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular