QuickView for RXFP1;jsessionid=254D02B343E6EF13479E09D99C1759B1 (gene)
- Gene Symbol:
- RXFP1
Homo sapiens - Full name:
- relaxin/insulin like family peptide receptor 1
- Synonyms:
- LGR7, RXFPR1, relaxin receptor 1, leucine-rich repeat-containing G protein-coupled receptor 7
- Genomic Location:
- Chr 4: 159662497-159792713
- Description:
-
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternative...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
4q32.1
GO Molecular Function
cation binding | transmembrane signaling receptor activity | G-protein coupled receptor activity | signaling receptor activity | ion binding | protein binding | peptide receptor activity | G-protein coupled peptide receptor activity | metal ion binding
GO Biological Process
intracellular signal transduction | response to hormone | hormone-mediated signaling pathway | cellular process | regulation of cellular process | G-protein coupled receptor activity | response to stimulus | G-protein coupled receptor signaling pathway | cellular response to hormone stimulus | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | adenylate cyclase-activating G-protein coupled receptor signaling pathway | regulation of catalytic activity | second-messenger-mediated signaling | cell communication | cyclic-nucleotide-mediated signaling | activation of adenylate cyclase activity | response to organic substance | cAMP-mediated signaling | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | signaling | G-protein coupled peptide receptor activity | cellular response to organic substance | signal transduction
GO Cellular Component
integral component of membrane | cell | intrinsic component of membrane | plasma membrane | integral component of plasma membrane | cell periphery | membrane | intrinsic component of plasma membrane
