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QuickView for Rab10 (gene)


Gene Symbol:
RAB10 Homo sapiens Homo sapiens
Full name:
RAB10, member RAS oncogene family
Synonyms:
ras-related protein Rab-10, GTP-binding protein RAB10, ras-related GTP-binding protein
Genomic Location:
Chr 2: 26110478-26213782
Description:
RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]).
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Canis lupus familiaris Gallus gallus Danio rerio Pan troglodytes Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
SP1_01 GTATTAT_MIR3693P PAX4_04 SMTTTTGT_UNKNOWN GATA1_01 RYTTCCTG_ETS2_B AAAGGGA_MIR204_MIR211 AAANWWTGC_UNKNOWN TGAGATT_MIR216 TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P
miRNA binding sites
(Source: TargetScan):
Predicted Gene Targets for miR-103 Predicted Gene Targets for miR-129 Predicted Gene Targets for miR-130 Predicted Gene Targets for miR-146 Predicted Gene Targets for miR-15 Predicted Gene Targets for miR-199 Predicted Gene Targets for miR-20 Predicted Gene Targets for miR-204 Predicted Gene Targets for miR-216 Predicted Gene Targets for miR-223
Cytogenetic Map:
chr 2
2p23.3


Transcripts Names
NM_016131
XM_024452565



GO Molecular Function

GDP binding | guanyl ribonucleotide binding | ribonucleoside binding | cadherin binding | cadherin binding involved in cell-cell adhesion | ribonucleotide binding | cell-cell adhesion mediator activity | nucleotide binding | hydrolase activity | myosin binding | carbohydrate derivative binding | pyrophosphatase activity | catalytic activity | cytoskeletal protein binding | anion binding | nucleoside-triphosphatase activity | purine nucleotide binding | ion binding | organic cyclic compound binding | GTPase activity | purine nucleoside binding | cell adhesion molecule binding | purine ribonucleoside triphosphate binding | protein binding | GTP binding | hydrolase activity, acting on acid anhydrides | nucleoside binding | cell adhesion mediator activity | purine ribonucleotide binding | myosin V binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | guanyl nucleotide binding | small molecule binding

GO Biological Process

cell morphogenesis | exocytosis | antigen processing and presentation | neuron projection morphogenesis | neutrophil activation | protein localization to cell periphery | intracellular signal transduction | regulation of localization | morphogenesis of an epithelium | protein localization to basolateral plasma membrane | establishment of localization | response to hormone | cell differentiation | nervous system development | cell part morphogenesis | neurogenesis | generation of neurons | intracellular transport | cellular process | secretion | leukocyte degranulation | localization | cell projection morphogenesis | protein transport | neuron development | protein localization to endoplasmic reticulum | cadherin binding involved in cell-cell adhesion | macromolecule localization | endomembrane system organization | membrane docking | establishment of localization in cell | response to peptide hormone | tissue development | Golgi to plasma membrane transport | morphogenesis of a polarized epithelium | regulation of cellular process | leukocyte activation | organelle localization | cell-cell adhesion mediator activity | polarized epithelial cell differentiation | small GTPase mediated signal transduction | epithelium development | cellular response to organonitrogen compound | establishment of cell polarity | cellular component organization | asymmetric neuroblast division | response to stimulus | cell morphogenesis involved in neuron differentiation | neutrophil degranulation | endosomal transport | intracellular protein transport | establishment of protein localization to plasma membrane | leukocyte activation involved in immune response | response to peptide | cellular localization | secretion by cell | somatic stem cell division | response to nitrogen compound | cellular response to hormone stimulus | system development | establishment of neuroblast polarity | multicellular organism development | cellular response to peptide hormone stimulus | neuroblast proliferation | leukocyte mediated immunity | cellular response to insulin stimulus | protein localization to plasma membrane | post-Golgi vesicle-mediated transport | stem cell proliferation | protein localization to membrane | axon development | organic substance transport | cellular response to peptide | stem cell division | peptide transport | vesicle-mediated transport | establishment or maintenance of neuroblast polarity | axonogenesis | protein localization to organelle | cell proliferation | cell division | neuronal stem cell division | regulated exocytosis | cell morphogenesis involved in differentiation | establishment or maintenance of cell polarity | peptide secretion | cell communication | asymmetric cell division | cell activation involved in immune response | myeloid cell activation involved in immune response | neutrophil activation involved in immune response | Golgi vesicle transport | establishment of protein localization to membrane | neuron differentiation | response to organic substance | tissue morphogenesis | Golgi to plasma membrane protein transport | regulation of exocytosis | establishment of protein localization to organelle | response to insulin | anatomical structure development | cell projection organization | cell fate commitment | establishment of protein localization to endoplasmic reticulum | Rab protein signal transduction | cellular protein localization | amide transport | regulation of vesicle-mediated transport | regulation of secretion | cell adhesion | immune response | neuron projection development | neural precursor cell proliferation | vesicle docking | establishment of protein localization | cell-cell adhesion | cell activation | neuroblast division | cell adhesion mediator activity | signaling | cell development | protein localization | anatomical structure morphogenesis | cellular macromolecule localization | vesicle docking involved in exocytosis | developmental process | organelle organization | regulation of transport | Ras protein signal transduction | neutrophil mediated immunity | response to organonitrogen compound | asymmetric stem cell division | epithelial cell differentiation | endoplasmic reticulum tubular network organization | immune system process | cellular response to organic substance | protein secretion | endoplasmic reticulum organization | establishment of protein localization to endoplasmic reticulum membrane | signal transduction | multicellular organismal process

GO Cellular Component

secretory granule | exocytic vesicle | intracellular membrane-bounded organelle | synapse | endocytic vesicle membrane | adherens junction | organelle membrane | focal adhesion | cytoplasmic vesicle | cell | tethering complex | cytoplasm | cell-substrate junction | intracellular organelle | endoplasmic reticulum | secretory granule membrane | cell-cell adherens junction | presynapse | cell-cell junction | endosome membrane | Golgi apparatus | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | cell projection | recycling endosome | secretory vesicle | phagocytic vesicle membrane | endomembrane system | endoplasmic reticulum membrane | plasma membrane | cilium | vesicle | transport vesicle | extracellular exosome | cytoplasmic region | synaptic vesicle | Golgi membrane | endosome | extracellular region | cell cortex | membrane-bounded organelle | extracellular vesicle | organelle | recycling endosome membrane | vesicle membrane | extracellular space | cell periphery | trans-Golgi network | cell-substrate adherens junction | insulin-responsive compartment | exocyst | endoplasmic reticulum tubular network | cytosol | intracellular vesicle | endocytic vesicle | intracellular | cell junction | membrane | cytoplasmic vesicle membrane | phagocytic vesicle