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QuickView for Rap2b (gene)


Gene Symbol:
RAP2B Homo sapiens Homo sapiens
Full name:
RAP2B, member of RAS oncogene family
Synonyms:
ras-related protein Rap-2b, small GTP binding protein
Genomic Location:
Chr 3: 154362719-154368955
Description:
This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced b...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Canis lupus familiaris Pan troglodytes Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 3
3q25.2


Transcripts Names
NM_002886
Protein Names
Q96EG5
P17964
P61225
Q9CXG0



GO Molecular Function

GDP binding | guanyl ribonucleotide binding | ribonucleoside binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | pyrophosphatase activity | catalytic activity | protein domain specific binding | anion binding | nucleoside-triphosphatase activity | purine nucleotide binding | ion binding | organic cyclic compound binding | GTPase activity | purine nucleoside binding | purine ribonucleoside triphosphate binding | protein binding | GTP binding | hydrolase activity, acting on acid anhydrides | nucleoside binding | purine ribonucleotide binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | guanyl nucleotide binding | small molecule binding

GO Biological Process

exocytosis | neutrophil activation | intracellular signal transduction | endothelial cell development | regulation of localization | establishment of localization | negative regulation of cellular process | cell differentiation | endothelial cell differentiation | positive regulation of phosphate metabolic process | cellular process | secretion | leukocyte degranulation | regulation of cell motility | localization | hemostasis | positive regulation of nitrogen compound metabolic process | negative regulation of cell migration | tissue development | negative regulation of cell motility | regulation of cellular process | leukocyte activation | regulation of metabolic process | small GTPase mediated signal transduction | positive regulation of cellular protein metabolic process | epithelium development | cellular component organization | platelet aggregation | response to stimulus | neutrophil degranulation | regulation of peptidyl-tyrosine phosphorylation | positive regulation of protein metabolic process | response to stress | leukocyte activation involved in immune response | epithelial cell development | secretion by cell | cellular component assembly | blood coagulation | regulation of protein tyrosine kinase activity | endothelium development | leukocyte mediated immunity | regulation of catalytic activity | regulation of phosphorylation | wound healing | platelet activation | regulation of protein autophosphorylation | cell projection assembly | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | establishment of endothelial barrier | regulation of nitrogen compound metabolic process | regulation of cell migration | Rap protein signal transduction | vesicle-mediated transport | regulation of cellular component movement | regulation of cellular protein metabolic process | microvillus assembly | regulated exocytosis | microvillus organization | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | cell activation involved in immune response | myeloid cell activation involved in immune response | regulation of protein metabolic process | neutrophil activation involved in immune response | regulation of protein phosphorylation | establishment of endothelial intestinal barrier | regulation of locomotion | coagulation | positive regulation of protein modification process | regulation of kinase activity | response to wounding | anatomical structure development | cell projection organization | regulation of body fluid levels | cell adhesion | immune response | negative regulation of cellular component movement | regulation of phosphate metabolic process | cell-cell adhesion | cell activation | signaling | cell development | positive regulation of phosphorylation | developmental process | positive regulation of protein autophosphorylation | Ras protein signal transduction | neutrophil mediated immunity | epithelial cell differentiation | positive regulation of metabolic process | immune system process | negative regulation of locomotion | homotypic cell-cell adhesion | signal transduction | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

secretory granule | occluding junction | organelle membrane | tertiary granule | cytoplasmic vesicle | cell | cytoplasm | intracellular organelle | membrane microdomain | secretory granule membrane | cell-cell junction | endosome membrane | cell-cell contact zone | recycling endosome | secretory vesicle | endomembrane system | plasma membrane | membrane raft | vesicle | extracellular exosome | specific granule | endosome | extracellular region | membrane-bounded organelle | extracellular vesicle | apical junction complex | organelle | recycling endosome membrane | vesicle membrane | extracellular space | cell periphery | bicellular tight junction | tertiary granule membrane | cytosol | intracellular vesicle | intracellular | cell junction | specific granule membrane | membrane | cytoplasmic vesicle membrane