QuickView for Rap2b (gene)

Gene Symbol:

RAP2B Homo sapiens

Full name:

RAP2B, member of RAS oncogene family

Synonyms:

ras-related protein Rap-2b, small GTP binding protein

Genomic Location:

Chr 3: 154362719-154368955

Description:

This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced b...

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This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Canis lupus familiaris ,  Pan troglodytes ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  PR_Q2 ,  GATTGGY_NFY_Q6_01 ,  P53_DECAMER_Q2 ,  HEN1_01 ,  CTAWWWATA_RSRFC4_Q2 ,  TTAYRTAA_E4BP4_01 ,  TAAWWATAG_RSRFC4_Q2 ,  YTAAYNGCT_UNKNOWN ,  WTTGKCTG_UNKNOWN ,  CAGCTG_AP4_Q5 ,  AACTTT_UNKNOWN

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Cytogenetic Map:

3q25.2

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