QuickView for Retinol-binding protein (gene)

Gene Symbol:

RBP4 Homo sapiens

Full name:

retinol binding protein 4

Synonyms:

MCOPCB10, RDCCAS, retinol-binding protein 4, PRBP, RBP, plasma retinol-binding protein, retinol binding protein 4, plasma, retinol-binding protein 4, interstitial

Genomic Location:

Chr 10: 95341583-95350983

Description:

This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blo...

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This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AP1_C ,  TGANTCA_AP1_C ,  HP1SITEFACTOR_Q6 ,  HNF1_C ,  GGGAGGRR_MAZ_Q6 ,  TATAAA_TATA_01 ,  AP1_01 ,  HNF3B_01 ,  TGCCAAR_NF1_Q6 ,  RTTTNNNYTGGM_UNKNOWN ,  AP1_Q4_01 ,  PAX4_01

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Cytogenetic Map:

10q23.33

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