QuickView for S1pr5 (gene)

Gene Symbol:

S1PR5 Homo sapiens

Full name:

sphingosine-1-phosphate receptor 5

Synonyms:

EDG8, Edg-8, S1P5, SPPR-1, SPPR-2, sphingosine 1-phosphate receptor 5, S1P receptor 5, S1P receptor Edg-8, endothelial differentiation G-protein-coupled receptor 8, endothelial differentiation, sphingolipid G-protein-coupled receptor, 8, sphingosine 1-phosphate receptor EDG8, sphingosine 1-phosphate receptor Edg-8

Genomic Location:

Chr 19: 10484623-10489112

Description:

The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coup...

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The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CEBP_Q2_01 ,  CEBPDELTA_Q6 ,  CEBPB_01 ,  SP1_Q4_01 ,  GGGCGGR_SP1_Q6 ,  SP1_Q6 ,  SP1_Q6_01 ,  SP1_Q2_01

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-384

Cytogenetic Map:

19p13.2

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