QuickView for SCD;jsessionid=3E7D68C3C095F75964C0308923553F86 (gene)

Gene Symbol:

SCD Homo sapiens

Full name:

stearoyl-CoA desaturase

Synonyms:

FADS5, MSTP008, SCD1, SCDOS, hSCD1, acyl-CoA desaturase, delta(9)-desaturase, fatty acid desaturase, predicted protein of HQ0998, stearoyl-CoA desaturase (delta-9-desaturase), stearoyl-CoA desaturase opposite strand

Genomic Location:

Chr 10: 102096762-102114578

Description:

This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detect...

View Full Description

This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Gallus gallus ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

PR_Q2 ,  TGGNNNNNNKCCAR_UNKNOWN ,  CATTGTYY_SOX9_B1 ,  TTTGTAG_MIR520D ,  GGGAGGRR_MAZ_Q6 ,  SOX9_B1 ,  NFY_Q6_01 ,  CTACCTC_LET7A_LET7B_LET7C_LET7D_LET7E_LET7F_MIR98_LET7G_LET7I ,  TGCCTTA_MIR124A ,  GTTTGTT_MIR495 ,  CTTTAAR_UNKNOWN ,  GTGCCTT_MIR506 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  CTTTGT_LEF1_Q2

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-495

Cytogenetic Map:

10q24.31

search → result