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QuickView for SCN11A (gene)


Gene Symbol:
SCN11A Homo sapiens Homo sapiens
Full name:
sodium voltage-gated channel alpha subunit 11
Synonyms:
FEPS3, HSAN7, NAV1.9, NaN, PN5, SCN12A, SNS-2, sodium channel protein type 11 subunit alpha, peripheral nerve sodium channel 5, sensory neuron sodium channel 2, sodium channel protein type XI subunit alpha, sodium channel, voltage-gated, type XI, alpha polypeptide, sodium channel, voltage-gated, type XI, alpha subunit, sodium channel, voltage-gated, type XII, alpha polypeptide, voltage-gated sodium channel subunit alpha Nav1.9
Genomic Location:
Chr 3: 38862264-38967056
Description:
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene fam...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 3
3p22.2





GO Molecular Function

voltage-gated ion channel activity | passive transmembrane transporter activity | voltage-gated sodium channel activity | transmembrane transporter activity | ion gated channel activity | cation transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | metal ion transmembrane transporter activity | sodium ion transmembrane transporter activity | sodium channel activity | cation channel activity | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

regulation of localization | establishment of localization | membrane depolarization during action potential | response to drug | voltage-gated ion channel activity | cellular process | localization | passive transmembrane transporter activity | metal ion transport | regulation of neurological system process | voltage-gated sodium channel activity | transmembrane transporter activity | response to stimulus | ion gated channel activity | neuronal action potential | regulation of membrane potential | ion transmembrane transport | regulation of sensory perception of pain | nervous system process | sodium ion transport | cation transmembrane transporter activity | monovalent inorganic cation transport | ion transmembrane transporter activity | cell communication | cation transmembrane transport | metal ion transmembrane transporter activity | membrane depolarization | sodium ion transmembrane transport | sodium ion transmembrane transporter activity | inorganic cation transmembrane transport | regulation of ion transmembrane transport | sodium channel activity | cation channel activity | transmembrane transport | action potential | signaling | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | voltage-gated channel activity | cation transport | channel activity | regulation of ion transport | regulation of transport | transmission of nerve impulse | ion channel activity | ion transport | substrate-specific channel activity | multicellular organismal process

GO Cellular Component

integral component of membrane | voltage-gated sodium channel complex | neuron projection | cell | plasma membrane protein complex | intrinsic component of membrane | protein-containing complex | cell projection | plasma membrane | C-fiber | vesicle | extracellular exosome | integral component of plasma membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | sodium channel complex | extracellular space | cell periphery | axon | transmembrane transporter complex | cation channel complex | ion channel complex | membrane | intrinsic component of plasma membrane