QuickView for SCN2B (gene)

Gene Symbol:

SCN2B Homo sapiens

Full name:

sodium voltage-gated channel beta subunit 2

Synonyms:

ATFB14, sodium channel subunit beta-2, neuronal voltage-gated sodium channel beta 2 subunit, sodium channel, voltage gated, type II beta subunit, sodium channel, voltage-gated, type II, beta polypeptide

Genomic Location:

Chr 11: 117538729-117552546

Description:

The protein encoded by this gene is the beta 2 subunit of the type II voltage-gated sodium channel. The encoded protein is involved in cell-cell adhesion and cell migration. Defects in this gene can be a cause of Brugada Syndrome, atrial fibrillation, or sudden infant death syndrome.

The protein encoded by this gene is the beta 2 subunit of the type II voltage-gated sodium channel. The encoded protein is involved in cell-cell adhesion and cell migration. Defects in this gene can be a cause of Brugada Syndrome, atrial fibrillation, or sudden infant death syndrome.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  CACTGCC_MIR34A_MIR34C_MIR449 ,  AAGCCAT_MIR135A_MIR135B ,  YGTCCTTGR_UNKNOWN ,  CAGGTCC_MIR492 ,  GGGACCA_MIR133A_MIR133B ,  CAGTGTT_MIR141_MIR200A ,  STAT6_01 ,  CTTTGA_LEF1_Q2 ,  STAT1_03 ,  AML1_01 ,  ATAGGAA_MIR202 ,  TEF1_Q6 ,  RP58_01 ,  CAGGTG_E12_Q6 ,  CTCAGGG_MIR125B_MIR125A ,  GTCTTCC_MIR7 ,  ACCAAAG_MIR9 ,  STAT5A_03 ,  RACCACAR_AML_Q6 ,  AGGGCCA_MIR328 ,  GTGCCTT_MIR506 ,  AML1_Q6 ,  WCAANNNYCAG_UNKNOWN ,  TATTATA_MIR374

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-125 ,  Predicted Gene Targets for miR-133 ,  Predicted Gene Targets for miR-135 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-328 ,  Predicted Gene Targets for miR-34 ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-7 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-374

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Cytogenetic Map:

11q23.3

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