QuickView for SDR16C5;jsessionid=CD5B302CFD36383474028B6743DD92B7 (gene)
- Gene Symbol:
- SDR16C5
Homo sapiens - Full name:
- short chain dehydrogenase/reductase family 16C member 5
- Synonyms:
- EPHD-2, RDH#2, RDH-E2, RDHE2, retSDR2, epidermal retinol dehydrogenase 2, epidermal retinal dehydrogenase 2, retinal short chain dehydrogenase reductase, retinal short-chain dehydrogenase reductase 2
- Genomic Location:
- Chr 8: 57375122-57395795
- Description:
-
This gene encodes a member of the short-chain alcohol dehydrogenase/reductase superfamily of proteins and is involved in the oxidation of retinol to retinaldehyde. The encoded protein is associated with the endoplasmic reticulum and is predicted to contain three transmembrane helices, suggesting that it is an integral membrane protein. It recognize...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
8q12.1
GO Molecular Function
transcription factor activity, transcription factor binding | retinol dehydrogenase activity | oxidoreductase activity, acting on CH-OH group of donors | transcription factor activity, RNA polymerase II transcription factor binding | transcriptional repressor activity, RNA polymerase II transcription factor binding | catalytic activity | protein binding | transcription factor binding | activating transcription factor binding | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | oxidoreductase activity
GO Biological Process
transcription factor activity, transcription factor binding | retinol dehydrogenase activity | oxidoreductase activity, acting on CH-OH group of donors | positive regulation of cellular component organization | negative regulation of cellular process | negative regulation of RNA biosynthetic process | regulation of organelle organization | cellular process | negative regulation of nucleic acid-templated transcription | regulation of histone modification | positive regulation of nitrogen compound metabolic process | transcription factor activity, RNA polymerase II transcription factor binding | negative regulation of peptidyl-lysine acetylation | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular lipid metabolic process | positive regulation of protein metabolic process | transcriptional repressor activity, RNA polymerase II transcription factor binding | alcohol metabolic process | positive regulation of protein deacetylation | retinol metabolic process | negative regulation of metabolic process | regulation of nucleic acid-templated transcription | organic hydroxy compound metabolic process | retinoid metabolic process | positive regulation of organelle organization | keratinocyte proliferation | lipid metabolic process | regulation of hormone levels | positive regulation of chromosome organization | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | small molecule metabolic process | regulation of transcription by RNA polymerase II | cell proliferation | regulation of cellular protein metabolic process | positive regulation of histone deacetylation | regulation of cellular metabolic process | regulation of protein deacetylation | regulation of protein metabolic process | regulation of RNA metabolic process | retinal metabolic process | cellular aldehyde metabolic process | positive regulation of protein modification process | epithelial cell proliferation | metabolic process | regulation of RNA biosynthetic process | oxidation-reduction process | negative regulation of transcription, DNA-templated | negative regulation of histone acetylation | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | positive regulation of histone modification | negative regulation of cellular protein metabolic process | diterpenoid metabolic process | regulation of chromosome organization | negative regulation of protein metabolic process | negative regulation of chromosome organization | regulation of transcription, DNA-templated | hormone metabolic process | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | isoprenoid metabolic process | regulation of histone acetylation | negative regulation of transcription by RNA polymerase II | negative regulation of protein acetylation | regulation of histone deacetylation | positive regulation of metabolic process | cellular metabolic process | oxidoreductase activity | regulation of cellular component organization | regulation of chromatin organization
GO Cellular Component
integral component of membrane | chromosome | intracellular membrane-bounded organelle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | endomembrane system | endoplasmic reticulum membrane | plasma membrane | chromatin | lipid droplet | membrane-bounded organelle | transcriptional repressor complex | nucleus | organelle | cell periphery | intracellular | membrane
