Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for SDS (gene)

Gene Symbol:
SDS Homo sapiens Homo sapiens
Full name:
serine dehydratase
SDH, L-serine dehydratase/L-threonine deaminase, L-serine ammonia-lyase, L-serine deaminase, L-serine dehydratase, L-threonine dehydratase, TDH
Genomic Location:
Chr 12: 112314633-112326075
This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver.
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 12

Transcripts Names
Protein Names

GO Molecular Function

cofactor binding | carbon-nitrogen lyase activity | vitamin binding | coenzyme binding | L-serine ammonia-lyase activity | hydro-lyase activity | lyase activity | pyridoxal phosphate binding | L-threonine ammonia-lyase activity | catalytic activity | anion binding | ammonia-lyase activity | identical protein binding | ion binding | organic cyclic compound binding | vitamin B6 binding | protein binding | protein homodimerization activity | protein dimerization activity | drug binding | heterocyclic compound binding | small molecule binding

GO Biological Process

L-threonine catabolic process to glycine | glycine metabolic process | glucose metabolic process | cellular amino acid catabolic process | cellular process | organic substance catabolic process | serine family amino acid metabolic process | cellular amino acid metabolic process | catabolic process | monocarboxylic acid metabolic process | carboxylic acid catabolic process | threonine metabolic process | cellular biosynthetic process | drug catabolic process | regulation of neurotransmitter levels | L-serine metabolic process | nitrogen compound metabolic process | hexose biosynthetic process | monosaccharide metabolic process | small molecule metabolic process | neurotransmitter metabolic process | carbohydrate biosynthetic process | biosynthetic process | pyruvate metabolic process | carbohydrate metabolic process | drug metabolic process | carboxylic acid metabolic process | threonine catabolic process | metabolic process | hexose metabolic process | gluconeogenesis | organic substance metabolic process | pyruvate biosynthetic process | organonitrogen compound catabolic process | organic acid metabolic process | serine family amino acid catabolic process | L-serine catabolic process | cellular metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | cytosol | intracellular