QuickView for SEPT3 (gene)
- Gene Symbol:
- SEPT3
Homo sapiens - Full name:
- septin 3
- Synonyms:
- SEP3, bK250D10.3, neuronal-specific septin-3
- Genomic Location:
- Chr 22: 40702877-40724171
- Description:
-
This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
- Orthologs:
- Mus musculus , Rattus norvegicus , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-103 , Predicted Gene Targets for miR-181 , Predicted Gene Targets for miR-204 , Predicted Gene Targets for miR-224 , Predicted Gene Targets for miR-23 , Predicted Gene Targets for miR-24 , Predicted Gene Targets for miR-323 , Predicted Gene Targets for miR-324-5p , Predicted Gene Targets for miR-328 , Predicted Gene Targets for miR-34
- Cytogenetic Map:
-
22q13.2
GO Molecular Function
structural molecule activity | guanyl ribonucleotide binding | ribonucleoside binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | pyrophosphatase activity | catalytic activity | anion binding | nucleoside-triphosphatase activity | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | GTPase activity | purine nucleoside binding | purine ribonucleoside triphosphate binding | protein binding | GTP binding | protein-containing complex scaffold activity | hydrolase activity, acting on acid anhydrides | nucleoside binding | purine ribonucleotide binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | guanyl nucleotide binding | small molecule binding
GO Biological Process
mitotic cytokinesis | cellular process | septin ring organization | cytoskeleton-dependent cytokinesis | cellular component organization | cellular component assembly | septin cytoskeleton organization | organelle assembly | cell cycle | cell projection assembly | cell division | cytokinesis | cellular protein-containing complex assembly | protein-containing complex assembly | mitotic cell cycle | cell projection organization | cilium assembly | cytoskeleton organization | cilium organization | organelle organization | septin ring assembly
GO Cellular Component
septin cytoskeleton | synapse | neuron projection | cell | cytoplasm | intracellular organelle | presynapse | protein-containing complex | cell projection | septin ring | presynaptic cytoskeleton | microtubule cytoskeleton | cytoplasmic region | cell cortex | organelle | cell periphery | septin filament array | septin complex | cytoskeleton | intracellular | cell junction
