QuickView for SGS1 (gene)
- Gene Symbol:
- SGS1
Saccharomyces cerevisiae - Full name:
- Nucleolar DNA helicase of the RecQ family involved in maintenance of genome integrity, regulates chromosome synapsis and meiotic crossing over; has similarity to human BLM and WRN helicases implicated in Bloom and Werner syndromes
- Synonyms:
- Sgs1, SGS1, sgs1, YMR190C
- Genomic Location:
- Chr XIII: 640914-645257
- Orthologs:
- Schizosaccharomyces pombe
- External Links:
- Entrez Gene
GO Molecular Function
four-way junction helicase activity | 3'-5' DNA helicase activity | nucleic acid binding | ribonucleotide binding | ATP-dependent DNA helicase activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | DNA binding | purine nucleotide binding | ATP-dependent helicase activity | ion binding | organic cyclic compound binding | ATP-dependent 3'-5' DNA helicase activity | purine ribonucleoside triphosphate binding | DNA helicase activity | protein binding | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | DNA-dependent ATPase activity | helicase activity | drug binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
double-strand break repair | response to radiation | intra-S DNA damage checkpoint | regulation of cell cycle process | telomere maintenance | regulation of mitotic recombination involved in replication fork processing | developmental process involved in reproduction | regulation of meiotic cell cycle | regulation of nuclear cell cycle DNA replication | mitotic recombination-dependent replication fork processing | negative regulation of cellular process | telomere capping | cell differentiation | regulation of DNA replication | regulation of organelle organization | four-way junction helicase activity | negative regulation of DNA metabolic process | negative regulation of meiotic cell cycle | resolution of recombination intermediates | cellular process | DNA-dependent DNA replication maintenance of fidelity | mitotic DNA integrity checkpoint | mitotic DNA replication maintenance of fidelity | cell cycle DNA replication | negative regulation of meiotic joint molecule formation | postreplication repair | 3'-5' DNA helicase activity | regulation of cell cycle | mitotic DNA replication | replicative cell aging | negative regulation of cellular metabolic process | DNA geometric change | anatomical structure homeostasis | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | DNA-dependent DNA replication | cellular component organization | ATP-dependent DNA helicase activity | response to UV | regulation of meiosis I | response to stimulus | UV-damage excision repair | regulation of DNA recombination | chromosome segregation | cellular response to light stimulus | response to stress | mating type determination | reproduction | cellular nitrogen compound metabolic process | telomere organization | negative regulation of metabolic process | cellular biosynthetic process | DNA recombination | meiotic chromosome segregation | resolution of mitotic recombination intermediates | DNA repair | negative regulation of reciprocal meiotic recombination | response to light stimulus | nitrogen compound metabolic process | reproductive process | replication fork processing | double-strand break repair via homologous recombination | mitotic DNA damage checkpoint | sister chromatid segregation | cellular response to DNA damage stimulus | gene conversion | negative regulation of meiotic nuclear division | cellular response to stress | DNA double-strand break processing | cell cycle | cellular response to radiation | regulation of nitrogen compound metabolic process | biosynthetic process | sex determination | regulation of DNA-dependent DNA replication | cellular response to UV | DNA duplex unwinding | nuclear chromosome segregation | DNA topological change | DNA strand elongation | regulation of cellular metabolic process | ATP-dependent 3'-5' DNA helicase activity | gene conversion at mating-type locus | homeostatic process | cell aging | regulation of mitotic cell cycle | DNA helicase activity | telomeric 3' overhang formation | regulation of meiotic nuclear division | DNA metabolic process | DNA unwinding involved in DNA replication | mitotic cell cycle | nuclear division | metabolic process | cell fate commitment | regulation of reciprocal meiotic recombination | regulation of mitotic recombination | negative regulation of mitotic cell cycle | nucleobase-containing compound metabolic process | organic substance metabolic process | gene conversion at mating-type locus, DNA double-strand break processing | mitotic recombination | telomere maintenance via recombination | mitotic nuclear division | negative regulation of cell cycle | negative regulation of DNA recombination | meiotic cell cycle | cellular macromolecule biosynthetic process | nuclear DNA replication | recombinational repair | developmental process | organelle organization | mating type switching | DNA conformation change | heterocycle metabolic process | chromosome organization | meiotic DNA double-strand break processing | mitotic cell cycle checkpoint | cellular metabolic process | negative regulation of cell cycle process | DNA damage checkpoint | cell cycle checkpoint | DNA replication | aging | mitotic sister chromatid segregation | regulation of cellular component organization | macromolecule metabolic process
GO Cellular Component
site of DNA damage | chromosome | intracellular membrane-bounded organelle | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | protein-containing complex | RecQ helicase-Topo III complex | nuclear chromosome | chromosome, telomeric region | site of double-strand break | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear chromosome, telomeric region | intracellular
