QuickView for SH3GL1 (gene)

Gene Symbol:

SH3GL1 Homo sapiens

Full name:

SH3 domain containing GRB2 like 1, endophilin A2

Synonyms:

CNSA1, EEN, SH3D2B, SH3P8, endophilin-A2, EEN fusion partner of MLL, SH3 domain protein 2B, SH3 domain-containing GRB2-like protein 1, SH3-containing Grb-2-like 1 protein, SH3-domain GRB2-like 1, endophilin-2, extra 11-19 leukemia fusion, extra eleven-nineteen leukemia fusion gene protein

Genomic Location:

Chr 19: 4311367-4351471

Description:

This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the m...

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This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Cytogenetic Map:

19p13.3

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