QuickView for SI (gene)

Gene Symbol:

SI Homo sapiens

Full name:

sucrase-isomaltase

Synonyms:

sucrase-isomaltase, intestinal, alpha-glucosidase, oligosaccharide alpha-1,6-glucosidase

Genomic Location:

Chr 3: 166179380-166278976

Description:

This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for ...

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This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

YTATTTTNR_MEF2_02 ,  IPF1_Q4 ,  CDX2_Q5 ,  TAATTA_CHX10_01 ,  AACTTT_UNKNOWN ,  HNF1_Q6 ,  RYTAAWNNNTGAY_UNKNOWN

Cytogenetic Map:

3q26.1

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