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QuickView for SLC22A5 (gene)


Gene Symbol:
SLC22A5 Homo sapiens Homo sapiens
Full name:
solute carrier family 22 member 5
Synonyms:
CDSP, OCTN2, solute carrier family 22 member 5, high-affinity sodium dependent carnitine cotransporter, organic cation/carnitine transporter 2
Genomic Location:
Chr 5: 131733343-131759205
Description:
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-de...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Bos taurus Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 5
5q31.1





GO Molecular Function

ammonium transmembrane transporter activity | ribonucleotide binding | transmembrane transporter activity | nucleotide binding | carbohydrate derivative binding | symporter activity | protein domain specific binding | ATP binding | anion binding | adenyl nucleotide binding | cation transmembrane transporter activity | active transmembrane transporter activity | purine nucleotide binding | transporter activity | ion transmembrane transporter activity | ion binding | organic cation transmembrane transporter activity | organic cyclic compound binding | drug transmembrane transporter activity | purine ribonucleoside triphosphate binding | protein binding | secondary active transmembrane transporter activity | purine ribonucleotide binding | PDZ domain binding | adenyl ribonucleotide binding | drug binding | carnitine transmembrane transporter activity | heterocyclic compound binding | quaternary ammonium group transmembrane transporter activity | small molecule binding

GO Biological Process

establishment of localization | organic cation transport | response to drug | sodium-dependent organic cation transport | cellular process | ammonium transmembrane transporter activity | localization | metal ion transport | anion transport | regulation of digestive system process | regulation of intestinal epithelial structure maintenance | interspecies interaction between organisms | transmembrane transporter activity | positive regulation of intestinal epithelial structure maintenance | response to stimulus | quorum sensing involved in interaction with host | symporter activity | ion transmembrane transport | organic substance transport | sodium ion transport | cation transmembrane transporter activity | amino-acid betaine transport | monovalent inorganic cation transport | active transmembrane transporter activity | positive regulation of digestive system process | ion transmembrane transporter activity | organic anion transport | organic cation transmembrane transporter activity | drug transmembrane transporter activity | cation transmembrane transport | carnitine transport | ammonium transmembrane transport | carnitine transmembrane transport | secondary active transmembrane transporter activity | drug transport | transmembrane transport | drug transmembrane transport | cation transport | ammonium transport | quaternary ammonium group transport | carnitine transmembrane transporter activity | ion transport | quaternary ammonium group transmembrane transporter activity

GO Cellular Component

brush border | apical plasma membrane | cell projection membrane | cell | brush border membrane | apical part of cell | cell projection | plasma membrane | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cell periphery | membrane