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QuickView for SLC22A6 (gene)


Gene Symbol:
SLC22A6 Homo sapiens Homo sapiens
Full name:
solute carrier family 22 member 6
Synonyms:
HOAT1, OAT1, PAHT, ROAT1, solute carrier family 22 member 6, PAH transporter, hPAHT, hROAT1, organic anion transporter 1, para-aminohippurate transporter, renal organic anion transporter 1, solute carrier family 22 (organic anion transporter), member 6
Genomic Location:
Chr 11: 62500645-62509045
Description:
The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 11
11q12.3





GO Molecular Function

inorganic anion exchanger activity | organic anion transmembrane transporter activity | anion transmembrane transporter activity | transmembrane transporter activity | inorganic anion transmembrane transporter activity | anion:anion antiporter activity | anion binding | chloride ion binding | antiporter activity | active transmembrane transporter activity | transporter activity | identical protein binding | ion transmembrane transporter activity | ion binding | protein binding | protein homodimerization activity | protein dimerization activity | secondary active transmembrane transporter activity

GO Biological Process

inorganic anion exchanger activity | protein homooligomerization | organic anion transmembrane transporter activity | establishment of localization | anion transmembrane transporter activity | response to drug | renal tubular secretion | cellular process | secretion | localization | dicarboxylic acid transport | anion transport | transmembrane transporter activity | cellular component organization | response to stimulus | inorganic anion transport | cellular component assembly | inorganic anion transmembrane transporter activity | anion:anion antiporter activity | response to nitrogen compound | protein complex oligomerization | ion transmembrane transport | organic substance transport | alpha-ketoglutarate transport | antiporter activity | active transmembrane transporter activity | response to methotrexate | organic acid transport | ion transmembrane transporter activity | organic anion transport | protein-containing complex assembly | response to organic substance | response to antineoplastic agent | anion transmembrane transport | cofactor transport | renal system process | secondary active transmembrane transporter activity | transmembrane transport | response to organic cyclic compound | carboxylic acid transport | response to organonitrogen compound | ion transport | multicellular organismal process

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | membrane microdomain | protein-containing complex | plasma membrane | membrane raft | vesicle | extracellular exosome | integral component of plasma membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cell periphery | basolateral plasma membrane | plasma membrane raft | caveola | membrane | intrinsic component of plasma membrane