QuickView for SLC6A2 (gene)

Gene Symbol:

SLC6A2 Homo sapiens

Full name:

solute carrier family 6 member 2

Synonyms:

NAT1, NET, NET1, SLC6A5, sodium-dependent noradrenaline transporter, neurotransmitter transporter, norepinephrine transporter, solute carrier family 6 (neurotransmitter transporter), member 2, solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2, solute carrier family 6 member 5

Genomic Location:

Chr 16: 54248057-54295201

Description:

This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheaded...

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This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TAAYNRNNTCC_UNKNOWN ,  TGCTGAY_UNKNOWN ,  CHOP_01

Cytogenetic Map:

16q12.2

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