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QuickView for SLC7A2 (gene)


Gene Symbol:
SLC7A2 Homo sapiens Homo sapiens
Full name:
solute carrier family 7 member 2
Synonyms:
ATRC2, CAT2, HCAT2, cationic amino acid transporter 2, low affinity cationic amino acid transporter 2, solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
Genomic Location:
Chr 8: 17440665-17472352
Description:
The protein encoded by this gene is a cationic amino acid transporter and a member of the APC (amino acid-polyamine-organocation) family of transporters. The encoded membrane protein is responsible for the cellular uptake of arginine, lysine and ornithine. Three transcript variants encoding different isoforms have been found for this gene.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Gallus gallus Canis lupus familiaris Danio rerio Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 8
8p22





GO Molecular Function

organic anion transmembrane transporter activity | anion transmembrane transporter activity | transmembrane transporter activity | organic acid transmembrane transporter activity | L-amino acid transmembrane transporter activity | L-ornithine transmembrane transporter activity | cation transmembrane transporter activity | high-affinity lysine transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | high-affinity L-ornithine transmembrane transporter activity | high-affinity arginine transmembrane transporter activity | drug transmembrane transporter activity | carboxylic acid transmembrane transporter activity | arginine transmembrane transporter activity | L-arginine transmembrane transporter activity | basic amino acid transmembrane transporter activity | amino acid transmembrane transporter activity | L-lysine transmembrane transporter activity | low-affinity L-arginine transmembrane transporter activity

GO Biological Process

ornithine transport | L-amino acid transport | organic anion transmembrane transporter activity | nitric oxide biosynthetic process | establishment of localization | regulation of immune system process | anion transmembrane transporter activity | defense response | response to drug | reactive oxygen species metabolic process | cellular process | production of molecular mediator involved in inflammatory response | localization | anion transport | cellular amino acid metabolic process | regulation of cellular process | leukocyte activation | transmembrane transporter activity | response to stimulus | response to stress | cellular nitrogen compound biosynthetic process | organic acid transmembrane transporter activity | L-ornithine import across plasma membrane | L-amino acid transmembrane transporter activity | cellular nitrogen compound metabolic process | reactive oxygen species biosynthetic process | cellular biosynthetic process | carboxylic acid transmembrane transport | L-lysine transmembrane transport | regulation of neurotransmitter levels | basic amino acid transmembrane transport | nitrogen compound metabolic process | L-ornithine transmembrane transporter activity | ion transmembrane transport | amino acid import | organic substance transport | cation transmembrane transporter activity | high-affinity lysine transmembrane transporter activity | small molecule metabolic process | organic acid transport | ion transmembrane transporter activity | high-affinity L-ornithine transmembrane transporter activity | high-affinity arginine transmembrane transporter activity | neurotransmitter metabolic process | biosynthetic process | organic anion transport | arginine transport | regulation of macrophage activation | drug transmembrane transporter activity | carboxylic acid transmembrane transporter activity | inflammatory response | L-arginine import across plasma membrane | L-lysine import across plasma membrane | L-arginine transport | amino acid transport | drug metabolic process | carboxylic acid metabolic process | cation transmembrane transport | reactive nitrogen species metabolic process | arginine transmembrane transporter activity | import into cell | L-arginine transmembrane transporter activity | amino acid transmembrane transport | anion transmembrane transport | organic acid transmembrane transport | L-alpha-amino acid transmembrane transport | metabolic process | macrophage activation | organic substance metabolic process | regulation of cell activation | basic amino acid transmembrane transporter activity | amino acid transmembrane transporter activity | nitric oxide production involved in inflammatory response | cell activation | drug transport | L-ornithine transmembrane transport | neurotransmitter biosynthetic process | transmembrane transport | organic acid metabolic process | drug transmembrane transport | carboxylic acid transport | basic amino acid transport | cation transport | arginine transmembrane transport | nitric oxide metabolic process | ion transport | L-arginine transmembrane transport | immune system process | cellular metabolic process | regulation of inflammatory response | L-lysine transmembrane transporter activity | low-affinity L-arginine transmembrane transporter activity | multicellular organismal process

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | plasma membrane | integral component of plasma membrane | cell periphery | cell junction | membrane | intrinsic component of plasma membrane