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QuickView for SLCO1A2 (gene)


Gene Symbol:
SLCO1A2 Homo sapiens Homo sapiens
Full name:
solute carrier organic anion transporter family member 1A2
Synonyms:
OATP, OATP-A, OATP1A2, SLC21A3, solute carrier organic anion transporter family member 1A2, OATP-1, organic anion transporting polypeptide A, organic anion-transporting polypeptide 1, sodium-independent organic anion transporter, solute carrier family 21 (organic anion transporter), member 3, solute carrier family 21 member 3
Genomic Location:
Chr 12: 21311651-21439638
Description:
This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Canis lupus familiaris Gallus gallus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 12
12p12.1





GO Molecular Function

bile acid transmembrane transporter activity | organic anion transmembrane transporter activity | anion transmembrane transporter activity | transmembrane transporter activity | organic acid transmembrane transporter activity | active transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | carboxylic acid transmembrane transporter activity | monocarboxylic acid transmembrane transporter activity | secondary active transmembrane transporter activity | lipid transporter activity | sodium-independent organic anion transmembrane transporter activity

GO Biological Process

bile acid transmembrane transporter activity | lipid transport | organic anion transmembrane transporter activity | establishment of localization | anion transmembrane transporter activity | monocarboxylic acid transport | localization | anion transport | macromolecule localization | transmembrane transporter activity | organic acid transmembrane transporter activity | organic hydroxy compound transport | carboxylic acid transmembrane transport | ion transmembrane transport | organic substance transport | active transmembrane transporter activity | organic acid transport | ion transmembrane transporter activity | organic anion transport | carboxylic acid transmembrane transporter activity | sodium-independent organic anion transport | anion transmembrane transport | organic acid transmembrane transport | lipid localization | bile acid and bile salt transport | monocarboxylic acid transmembrane transporter activity | secondary active transmembrane transporter activity | transmembrane transport | carboxylic acid transport | lipid transporter activity | ion transport | sodium-independent organic anion transmembrane transporter activity

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | plasma membrane | integral component of plasma membrane | cell periphery | membrane | intrinsic component of plasma membrane