QuickView for SLFN14;jsessionid=9AD3CBEBBEBF837078E3B4360BD07438 (gene)
- Gene Symbol:
- SLFN14
Homo sapiens - Full name:
- schlafen family member 14
- Synonyms:
- BDPLT20, protein SLFN14
- Genomic Location:
- Chr 17: 30899371-30909194
- Description:
-
The protein encoded by this gene plays an important role in platelet formation and function. Defects in this gene are a cause of thrombocytopenia with excessive bleeding.
- Orthologs:
- Mus musculus , Rattus norvegicus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
17q12
| Transcripts Names |
|---|
| XM_496207 |
| XM_940940 |
| XM_001715630 |
| NM_001129820 |
| XM_017024577 |
| XM_017024576 |
| XM_017024579 |
| XM_017024578 |
GO Molecular Function
nuclease activity | protein-containing complex binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ribonuclease activity | catalytic activity | ribonucleoprotein complex binding | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | hydrolase activity, acting on ester bonds | ion binding | organic cyclic compound binding | ribosome binding | purine ribonucleoside triphosphate binding | endoribonuclease activity | endonuclease activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | small molecule binding
GO Biological Process
RNA metabolic process | nuclease activity | response to metal ion | cell differentiation | cellular process | organic substance catabolic process | response to magnesium ion | cell maturation | response to inorganic substance | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | mRNA catabolic process | cellular response to metal ion | response to stimulus | cellular response to inorganic substance | cellular nitrogen compound metabolic process | nucleic acid phosphodiester bond hydrolysis | negative regulation of metabolic process | mRNA metabolic process | ribonuclease activity | nucleobase-containing compound catabolic process | nitrogen compound metabolic process | regulation of gene expression | RNA catabolic process | response to manganese ion | rRNA metabolic process | platelet maturation | rRNA catabolic process | aromatic compound catabolic process | endoribonuclease activity | cellular macromolecule catabolic process | anatomical structure development | metabolic process | RNA phosphodiester bond hydrolysis, endonucleolytic | developmental maturation | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of gene expression | RNA phosphodiester bond hydrolysis | endonuclease activity | cell development | developmental process | cellular response to manganese ion | ncRNA metabolic process | heterocycle metabolic process | cellular metabolic process | macromolecule metabolic process | cellular response to magnesium ion
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular
