QuickView for SOAT2;jsessionid=C36D460C8505FD27BBBBB3A9682746E4 (gene)

Gene Symbol:

SOAT2 Homo sapiens

Full name:

sterol O-acyltransferase 2

Synonyms:

ACACT2, ACAT2, ARGP2, sterol O-acyltransferase 2, ACAT-2, acyl Co-A: cholesterol acyltransferase 2, acyl coenzyme A:cholesterol acyltransferase 2, acyl-CoA:cholesterol acyltransferase 2, cholesterol acyltransferase 2

Genomic Location:

Chr 12: 51783541-51804590

Description:

Summary:This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside th...

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Summary:This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside the cell. The enzyme is implicated in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low density lipoprotein (VLDL). Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

HNF1_01 ,  YATTNATC_UNKNOWN ,  GGATTA_PITX2_Q2 ,  CTTTGT_LEF1_Q2 ,  CRX_Q4

Cytogenetic Map:

12q13.13

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