QuickView for SORBS1;jsessionid=40D3F6E198E93C5894B340CA6F7FEC22 (gene)

Gene Symbol:

SORBS1 Homo sapiens

Full name:

sorbin and SH3 domain containing 1

Synonyms:

CAP, FLAF2, R85FL, SH3D5, SH3P12, SORB1, sorbin and SH3 domain-containing protein 1, Fas-ligand associated factor 2, SH3 domain protein 5, c-Cbl associated protein, ponsin

Genomic Location:

Chr 10: 97061520-97311161

Description:

This gene encodes a CBL-associated protein which functions in the signaling and stimulation of insulin. Mutations in this gene may be associated with human disorders of insulin resistance. Alternative splicing results in multiple transcript variants.

This gene encodes a CBL-associated protein which functions in the signaling and stimulation of insulin. Mutations in this gene may be associated with human disorders of insulin resistance. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

IRF1_01 ,  MCAATNNNNNGCG_UNKNOWN ,  TTTGCAG_MIR518A2 ,  GATA3_01 ,  YATGNWAAT_OCT_C ,  ATF4_Q2 ,  YATTNATC_UNKNOWN ,  E2F_Q6_01 ,  ARP1_01 ,  SRY_01 ,  ACTTTAT_MIR1425P ,  HNF1_C ,  SREBP1_Q6 ,  CTTTGA_LEF1_Q2 ,  IRF1_Q6 ,  HEB_Q6 ,  TCF4_Q5 ,  WTGAAAT_UNKNOWN ,  GGGAGGRR_MAZ_Q6 ,  LEF1_Q6 ,  LEF1_Q2 ,  CACCCBINDINGFACTOR_Q6 ,  RP58_01 ,  CAGGTG_E12_Q6 ,  AP4_Q6 ,  AP4_01 ,  GATA6_01 ,  NERF_Q2 ,  CTTTAAR_UNKNOWN ,  E47_01 ,  MEIS1_01 ,  TTGTTT_FOXO4_01 ,  GR_01 ,  AP4_Q6_01 ,  WWTAAGGC_UNKNOWN ,  GTGGGTGK_UNKNOWN ,  TAL1BETAITF2_01 ,  ICSBP_Q6 ,  CAGCTG_AP4_Q5 ,  ISRE_01 ,  AACTTT_UNKNOWN ,  TGACATY_UNKNOWN ,  ATGAAGG_MIR205 ,  STTTCRNTTT_IRF_Q6 ,  IRF2_01 ,  TCF11_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-142-5p ,  Predicted Gene Targets for miR-205 ,  Predicted Gene Targets for miR-216 ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-433-3p

Cytogenetic Map:

10q24.1

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