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QuickView for SPOCK1 (gene)


Gene Symbol:
SPOCK1 Homo sapiens Homo sapiens
Full name:
SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1
Synonyms:
SPOCK, TESTICAN, TIC1, testican-1, sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
Genomic Location:
Chr 5: 136338886-136862917
Description:
This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 5
5q31.2


Transcripts Names
NM_004598
Protein Names
Q9UCL8
Q08629
B3KSW3
Q59EW0
Q8N630



GO Molecular Function

endopeptidase inhibitor activity | cation binding | protein-containing complex binding | enzyme inhibitor activity | molecular function regulator | extracellular matrix binding | collagen binding | ion binding | serine-type endopeptidase inhibitor activity | calcium ion binding | metalloendopeptidase inhibitor activity | peptidase inhibitor activity | enzyme regulator activity | metal ion binding | cysteine-type endopeptidase inhibitor activity

GO Biological Process

endopeptidase inhibitor activity | cell motility | regulation of neurogenesis | regulation of cell development | neuron migration | negative regulation of cellular process | cell differentiation | nervous system development | neurogenesis | generation of neurons | negative regulation of proteolysis | cellular process | localization | central nervous system neuron differentiation | regulation of proteolysis | regulation of neuron projection development | negative regulation of cellular metabolic process | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | enzyme inhibitor activity | negative regulation of cell adhesion | negative regulation of neuron projection development | negative regulation of metabolic process | regulation of cell adhesion | molecular function regulator | locomotion | system development | multicellular organism development | negative regulation of catalytic activity | cell migration | regulation of peptidase activity | regulation of catalytic activity | negative regulation of peptidase activity | regulation of neuron differentiation | regulation of nitrogen compound metabolic process | regulation of cell-substrate adhesion | regulation of cellular protein metabolic process | negative regulation of cell-substrate adhesion | regulation of cellular metabolic process | regulation of protein metabolic process | neuron differentiation | regulation of growth | negative regulation of cell projection organization | anatomical structure development | cell adhesion | negative regulation of neuron differentiation | negative regulation of cellular protein metabolic process | serine-type endopeptidase inhibitor activity | negative regulation of protein metabolic process | negative regulation of molecular function | metalloendopeptidase inhibitor activity | peptidase inhibitor activity | enzyme regulator activity | regulation of endopeptidase activity | regulation of nervous system development | regulation of developmental process | developmental process | regulation of cell growth | negative regulation of hydrolase activity | central nervous system development | regulation of cell projection organization | cysteine-type endopeptidase inhibitor activity | negative regulation of cell development | negative regulation of cell differentiation | regulation of cellular component organization | negative regulation of endopeptidase activity | negative regulation of neurogenesis | multicellular organismal process

GO Cellular Component

synapse | neuron projection | neuromuscular junction | cell | cytoplasm | main axon | cell projection | postsynapse | postsynaptic density | asymmetric synapse | node of Ranvier | extracellular region | organelle | postsynaptic specialization | sarcoplasm | extracellular space | axon | intracellular