QuickView for SPRED2 (gene)

Gene Symbol:

SPRED2 Homo sapiens

Full name:

sprouty related EVH1 domain containing 2

Synonyms:

Spred-2, sprouty-related, EVH1 domain-containing protein 2, sprouty protein with EVH-1 domain 2, related sequence

Genomic Location:

Chr 2: 65391489-65512815

Description:

SPRED2 is a member of the Sprouty (see SPRY1; MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1; MIM 176948) (Nonami et al., 2004 [PubMed 15465815]).

SPRED2 is a member of the Sprouty (see SPRY1; MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1; MIM 176948) (Nonami et al., 2004 [PubMed 15465815]).

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  CREB_Q4_01 ,  GATA3_01 ,  ATGTACA_MIR493 ,  E2F1_Q4 ,  CREB_Q3 ,  GGGAGGRR_MAZ_Q6 ,  ATF_B ,  TFIII_Q6 ,  TGTATGA_MIR4853P ,  RP58_01 ,  NFY_Q6_01 ,  ATF_01 ,  CAGGTG_E12_Q6 ,  CAGCTTT_MIR320 ,  AGTCAGC_MIR345 ,  CREB_02 ,  GGGCGGR_SP1_Q6 ,  GTATGAT_MIR154_MIR487 ,  NERF_Q2 ,  ACTGCAG_MIR173P ,  KCCGNSWTTT_UNKNOWN ,  ATF1_Q6 ,  SCGGAAGY_ELK1_02 ,  RGAGGAARY_PU1_Q6 ,  KMCATNNWGGA_UNKNOWN ,  ETS1_B ,  ELF1_Q6 ,  CREB_Q2_01 ,  AAGCACA_MIR218

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-320 ,  Predicted Gene Targets for miR-329 ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-485-3p ,  Predicted Gene Targets for miR-493-5p ,  Predicted Gene Targets for miR-496

Cytogenetic Map:

2p14

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