QuickView for SRSF7;jsessionid=88BFBC24181686B5F95C308A74B592B1 (gene)

Gene Symbol:

SRSF7 Homo sapiens

Full name:

serine and arginine rich splicing factor 7

Synonyms:

9G8, AAG3, SFRS7, serine/arginine-rich splicing factor 7, SR splicing factor 7, aging-associated protein 3, splicing factor 9G8, splicing factor, arginine/serine-rich 7, 35kDa

Genomic Location:

Chr 2: 38824245-38832005

Description:

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates ...

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The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

SP1_01 ,  HNF1_01 ,  FOXJ2_02 ,  OCT1_04 ,  AREB6_02 ,  TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D ,  E2F4DP1_01 ,  CTTTGCA_MIR527 ,  IPF1_Q4 ,  ATCMNTCCGY_UNKNOWN ,  WGTTNNNNNAAA_UNKNOWN ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  GTAAACC_MIR2995P ,  HNF1_C ,  PBX1_01 ,  GCCATNTTG_YY1_Q6 ,  TATAAA_TATA_01 ,  E2F_Q6 ,  FOXO3_01 ,  CAGGTG_E12_Q6 ,  CAGCTTT_MIR320 ,  LHX3_01 ,  TGCGCANK_UNKNOWN ,  E2F_Q4 ,  GGGCGGR_SP1_Q6 ,  AREB6_01 ,  E2F1DP2_01 ,  AAGGGAT_MIR188 ,  ATGTTTC_MIR494 ,  E2F1_Q3_01 ,  NKX25_02 ,  NRF1_Q6 ,  E2F1DP1_01 ,  AREB6_03 ,  POU3F2_02 ,  TAATTA_CHX10_01 ,  TTGTTT_FOXO4_01 ,  E2F1DP1RB_01 ,  PIT1_Q6 ,  E2F_02 ,  YTAATTAA_LHX3_01 ,  IK1_01 ,  AGGGCAG_MIR18A ,  E2F1_Q3 ,  E2F4DP2_01 ,  CTTTGT_LEF1_Q2 ,  RCGCANGCGY_NRF1_Q6 ,  KTGGYRSGAA_UNKNOWN ,  SRY_02 ,  CTAGGAA_MIR384 ,  DR4_Q2 ,  HNF1_Q6 ,  TATTATA_MIR374 ,  CP2_01 ,  E2F1_Q6 ,  SGCGSSAAA_E2F1DP2_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-1 ,  Predicted Gene Targets for miR-18 ,  Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-186 ,  Predicted Gene Targets for miR-192 ,  Predicted Gene Targets for miR-299 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-320 ,  Predicted Gene Targets for miR-325 ,  Predicted Gene Targets for miR-328 ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-485-5p ,  Predicted Gene Targets for miR-494 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-188 ,  Predicted Gene Targets for miR-374 ,  Predicted Gene Targets for miR-375 ,  Predicted Gene Targets for miR-380-5p ,  Predicted Gene Targets for miR-384 ,  Predicted Gene Targets for miR-452 ,  Predicted Gene Targets for miR-488 ,  Predicted Gene Targets for miR-505 ,  Predicted Gene Targets for miR-544 ,  Predicted Gene Targets for miR-378

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Cytogenetic Map:

2p22.1

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