QuickView for SSR1;jsessionid=595BAA89C4BBB6CBABB102C00830CE7F (gene)

Gene Symbol:

SSR1 Homo sapiens

Full name:

signal sequence receptor subunit 1

Synonyms:

TRAPA, translocon-associated protein subunit alpha, SSR alpha subunit, SSR-alpha, TRAP alpha, signal sequence receptor subunit alpha, signal sequence receptor, alpha, translocon-associated protein alpha subunit

Genomic Location:

Chr 6: 7232803-7258434

Description:

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylatio...

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The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. Multiple transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Canis lupus familiaris ,  Gallus gallus ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AAGCCAT_MIR135A_MIR135B ,  TGANNYRGCA_TCF11MAFG_01 ,  MYCMAX_03 ,  CACGTG_MYC_Q2 ,  MAX_01 ,  GGGAGGRR_MAZ_Q6 ,  TGCACTG_MIR148A_MIR152_MIR148B ,  GTTTGTT_MIR495 ,  ACTACCT_MIR196A_MIR196B ,  GGGCGGR_SP1_Q6 ,  USF_01 ,  NCX_01 ,  CEBP_Q3 ,  USF_Q6_01 ,  AACTTT_UNKNOWN ,  USF_02 ,  CCACACA_MIR147 ,  AAGCACA_MIR218

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-135 ,  Predicted Gene Targets for miR-148 ,  Predicted Gene Targets for miR-196 ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-30-3p ,  Predicted Gene Targets for miR-495 ,  Predicted Gene Targets for miR-496 ,  Predicted Gene Targets for miR-544

Cytogenetic Map:

6p24.3

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