QuickView for STK26;jsessionid=58322502BA86313AB0CEA76B6EB3C362 (gene)

Gene Symbol:

STK26 Homo sapiens

Full name:

serine/threonine kinase 26

Synonyms:

MASK, MST4, serine/threonine-protein kinase 26, Mst3 and SOK1-related kinase, STE20-like kinase 4, STE20-like kinase MST4, mammalian Ste20-like protein kinase 4, mammalian sterile 20-like 4, serine/threonine protein kinase 26, serine/threonine protein kinase MST4, serine/threonine-protein kinase MASK

Genomic Location:

Chr X: 130984926-131037652

Description:

The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding...

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The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  SYATTGTG_UNKNOWN ,  YTATTTTNR_MEF2_02 ,  CAGGTG_E12_Q6 ,  TCCATTKW_UNKNOWN

Cytogenetic Map:

Xq26.2

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