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QuickView for STT3A (gene)


Gene Symbol:
STT3A Homo sapiens Homo sapiens
Full name:
STT3A, catalytic subunit of the oligosaccharyltransferase complex
Synonyms:
ITM1, STT3-A, TMC, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A, B5, STT3, subunit of the oligosaccharyltransferase complex, homolog A, STT3A, cataylic subunit of the oligosaccharyltransferase complex, STT3A, subunit of the oligosaccharyltransferase complex (catalytic), dolichyl-diphosphooligosaccharide protein glycotransferase, integral membrane protein 1, integral transmembrane protein 1, oligosaccharyl transferase subunit STT3A, transmembrane conserved, transmembrane protein TMC
Genomic Location:
Chr 11: 124967967-124996168
Description:
The protein encoded by this gene is a catalytic subunit of the N-oligosaccharyltransferase (OST) complex, which functions in the endoplasmic reticulum to transfer glycan chains to asparagine residues of target proteins. A separate complex containing a similar catalytic subunit with an overlapping function also exists. Multiple transcript variants e...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 11
11q24.2





GO Molecular Function

cation binding | dolichyl-diphosphooligosaccharide-protein glycotransferase activity | catalytic activity | transferase activity, transferring glycosyl groups | ion binding | protein binding | transferase activity, transferring hexosyl groups | transferase activity | oligosaccharyl transferase activity | metal ion binding

GO Biological Process

peptidyl-amino acid modification | cellular process | glycoprotein biosynthetic process | protein N-linked glycosylation via asparagine | co-translational protein modification | carbohydrate derivative biosynthetic process | protein modification process | macromolecule glycosylation | cellular biosynthetic process | macromolecule modification | nitrogen compound metabolic process | biosynthetic process | protein metabolic process | metabolic process | organic substance metabolic process | cellular protein metabolic process | protein N-linked glycosylation | cellular macromolecule biosynthetic process | cellular protein modification process | carbohydrate derivative metabolic process | protein glycosylation | glycosylation | cellular metabolic process | glycoprotein metabolic process | macromolecule metabolic process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | catalytic complex | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | endomembrane system | endoplasmic reticulum membrane | transferase complex | membrane-bounded organelle | organelle | intracellular | membrane | oligosaccharyltransferase complex