kinase binding | ubiquitin-ubiquitin ligase activity | enzyme binding | signaling receptor binding | catalytic activity | chaperone binding | protein domain specific binding | Hsp70 protein binding | ubiquitin-like protein ligase binding | ubiquitin-like protein transferase activity | protein binding, bridging | identical protein binding | ubiquitin protein ligase activity | TPR domain binding | molecular adaptor activity | protein binding | protein homodimerization activity | misfolded protein binding | ubiquitin protein ligase binding | protein dimerization activity | ubiquitin-protein transferase activity | G-protein coupled receptor binding | transferase activity | ubiquitin-like protein ligase activity | Hsp90 protein binding | heat shock protein binding | SMAD binding
cellular response to decreased oxygen levels | response to endoplasmic reticulum stress | positive regulation of cellular component organization | proteolysis | regulation of transforming growth factor beta receptor signaling pathway | negative regulation of cellular process | ubiquitin-ubiquitin ligase activity | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | response to misfolded protein | positive regulation of protein catabolic process | cellular process | protein K63-linked ubiquitination | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | regulation of ubiquitin-protein transferase activity | negative regulation of signaling | endoplasmic reticulum unfolded protein response | response to hypoxia | regulation of proteolysis | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of binding | regulation of cellular process | regulation of metabolic process | catabolic process | regulation of protein complex assembly | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | cellular response to unfolded protein | response to topologically incorrect protein | cellular aromatic compound metabolic process | cellular response to topologically incorrect protein | positive regulation of cellular protein catabolic process | response to stimulus | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | cellular response to hypoxia | response to stress | regulation of protein ubiquitination | positive regulation of proteolysis involved in cellular protein catabolic process | cellular protein catabolic process | response to temperature stimulus | positive regulation of proteolysis | cellular nitrogen compound metabolic process | proteasomal protein catabolic process | positive regulation of chaperone-mediated protein complex assembly | response to ischemia | ERBB signaling pathway | protein modification process | macromolecule modification | negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | regulation of steroid metabolic process | ERBB2 signaling pathway | DNA repair | negative regulation of cellular response to transforming growth factor beta stimulus | response to nitrogen compound | response to oxygen levels | nitrogen compound metabolic process | regulation of signal transduction | regulation of protein stability | cellular response to DNA damage stimulus | regulation of catalytic activity | regulation of hormone levels | cellular response to stress | protein catabolic process | cellular response to heat | positive regulation of cellular metabolic process | cellular response to oxygen levels | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | enzyme linked receptor protein signaling pathway | negative regulation of cellular response to growth factor stimulus | positive regulation of protein complex assembly | ubiquitin protein ligase activity | negative regulation of binding | regulation of hormone metabolic process | regulation of cellular protein metabolic process | positive regulation of proteasomal protein catabolic process | protein maturation | cell communication | negative regulation of protein binding | regulation of cellular metabolic process | transmembrane receptor protein serine/threonine kinase signaling pathway | regulation of protein metabolic process | regulation of cellular response to growth factor stimulus | proteasome-mediated ubiquitin-dependent protein catabolic process | positive regulation of molecular function | regulation of proteasomal ubiquitin-dependent protein catabolic process | protein polyubiquitination | ERAD pathway | ubiquitin-dependent SMAD protein catabolic process | protein metabolic process | negative regulation of transforming growth factor beta receptor signaling pathway | positive regulation of protein modification process | response to organic substance | protein ubiquitination | DNA metabolic process | cellular macromolecule catabolic process | protein autoubiquitination | cell surface receptor signaling pathway | metabolic process | positive regulation of ubiquitin-dependent protein catabolic process | ubiquitin-protein transferase activity | regulation of protein catabolic process | protein quality control for misfolded or incompletely synthesized proteins | regulation of proteasomal protein catabolic process | nucleobase-containing compound metabolic process | positive regulation of cellular component biogenesis | organic substance metabolic process | gene expression | response to heat | protein modification by small protein conjugation or removal | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of protein binding | cellular protein metabolic process | response to unfolded protein | cellular protein modification process | response to organonitrogen compound | heterocycle metabolic process | positive regulation of ubiquitin-protein transferase activity | ubiquitin-dependent ERAD pathway | transmembrane receptor protein tyrosine kinase signaling pathway | regulation of lipid metabolic process | positive regulation of metabolic process | cellular response to misfolded protein | cellular metabolic process | regulation of glucocorticoid metabolic process | cellular response to organic substance | modification-dependent protein catabolic process | regulation of ubiquitin-dependent protein catabolic process | positive regulation of protein ubiquitination | regulation of cellular component organization | signal transduction | regulation of signaling | macromolecule metabolic process
nuclear inclusion body | supramolecular fiber | intracellular membrane-bounded organelle | catalytic complex | sarcomere | cell | nuclear lumen | myofibril | cytoplasm | intracellular organelle | endoplasmic reticulum | ubiquitin ligase complex | contractile fiber | inclusion body | protein-containing complex | endomembrane system | nucleoplasm | transferase complex | ubiquitin conjugating enzyme complex | membrane-bounded organelle | chaperone complex | nucleus | organelle | I band | membrane-enclosed lumen | Z disc | cytosol | intracellular | supramolecular complex