QuickView for Snu114 (gene)
- Gene Symbol:
- SNU114
Saccharomyces cerevisiae - Full name:
- GTPase component of U5 snRNP involved in mRNA splicing via spliceosome; binds directly to U5 snRNA; proposed to be involved in conformational changes of the spliceosome; similarity to ribosomal translocation factor EF-2
- Synonyms:
- GIN10, SNU114, Snu114, YKL173W
- Genomic Location:
- Chr XI: 122522-125548
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
guanyl ribonucleotide binding | ribonucleoside binding | nucleic acid binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | pyrophosphatase activity | catalytic activity | anion binding | nucleoside-triphosphatase activity | purine nucleotide binding | ion binding | organic cyclic compound binding | GTPase activity | purine nucleoside binding | U5 snRNA binding | purine ribonucleoside triphosphate binding | snRNA binding | GTP binding | hydrolase activity, acting on acid anhydrides | nucleoside binding | purine ribonucleotide binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | guanyl nucleotide binding | small molecule binding | RNA binding
GO Biological Process
RNA metabolic process | spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) | RNA processing | translational elongation | cellular process | spliceosomal snRNP assembly | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | RNA splicing | peptide biosynthetic process | RNA splicing, via transesterification reactions | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cellular component assembly | mRNA metabolic process | cellular biosynthetic process | nitrogen compound metabolic process | cellular amide metabolic process | spliceosomal tri-snRNP complex assembly | translation | biosynthetic process | cellular protein-containing complex assembly | peptide metabolic process | spliceosomal conformational changes to generate catalytic conformation | protein-containing complex assembly | protein metabolic process | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | amide biosynthetic process | ribonucleoprotein complex assembly | cellular protein metabolic process | cellular macromolecule biosynthetic process | heterocycle metabolic process | generation of catalytic spliceosome for first transesterification step | ribonucleoprotein complex biogenesis | cellular metabolic process | mRNA processing | mRNA splicing, via spliceosome | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | small nuclear ribonucleoprotein complex | U4/U6 x U5 tri-snRNP complex | cell | spliceosomal snRNP complex | intracellular organelle | protein-containing complex | ribonucleoprotein complex | membrane-bounded organelle | nucleus | organelle | U5 snRNP | intracellular
