QuickView for Spd (gene)

Gene Symbol:

HOXD13 Homo sapiens

Full name:

homeobox D13

Synonyms:

BDE, BDSD, HOX4I, SPD, SPD1, homeobox protein Hox-D13, homeo box 4I, homeo box D13, homeobox protein Hox-4I

Genomic Location:

Chr 2: 176665778-176668912

Description:

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arr...

View Full Description

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. Mutations in this particular gene cause synpolydactyly.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

PBX1_02 ,  SRF_Q6 ,  ZIC3_01 ,  IRF1_Q6 ,  NKX22_01 ,  CTTTGTA_MIR524 ,  RGAANNTTC_HSF1_01 ,  TITF1_Q3 ,  GGGCGGR_SP1_Q6 ,  TTGTTT_FOXO4_01 ,  IRF7_01 ,  ZIC2_01 ,  GTGGGTGK_UNKNOWN ,  GGCCAGT_MIR193A_MIR193B ,  CTTTGT_LEF1_Q2 ,  CCAWWNAAGG_SRF_Q4 ,  OLF1_01

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-193 ,  Predicted Gene Targets for miR-26

Cytogenetic Map:

2q31.1

search → result