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QuickView for Stx3 (gene)


Gene Symbol:
STX3 Homo sapiens Homo sapiens
Full name:
syntaxin 3
Synonyms:
STX3A, syntaxin-3, syntaxin 3A
Genomic Location:
Chr 11: 59279465-59326755
Description:
The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing results in multiple transcript variants.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 11
11q12.1





GO Molecular Function

fatty acid binding | long-chain fatty acid binding | SNAP receptor activity | carboxylic acid binding | lipid binding | arachidonic acid binding | anion binding | icosatetraenoic acid binding | ion binding | protein binding | SNARE binding | organic acid binding | small molecule binding

GO Biological Process

synaptic vesicle exocytosis | positive regulation of locomotion | exocytosis | response to cytokine | neurotransmitter secretion | protein localization to cell periphery | regulation of cellular localization | regulation of localization | organelle fusion | establishment of localization | membrane fusion | regulation of protein localization to membrane | cell differentiation | nervous system development | neurogenesis | positive regulation of cell adhesion | generation of neurons | membrane organization | intracellular transport | cellular process | secretion | establishment of organelle localization | localization | positive regulation of synaptic transmission | protein transport | chemical synaptic transmission | neuron development | SNAP receptor activity | exocytic insertion of neurotransmitter receptor to postsynaptic membrane | macromolecule localization | regulation of chemotaxis | protein localization to postsynaptic membrane | membrane docking | establishment of localization in cell | regulation of cellular process | organelle localization | cellular component organization | response to stimulus | regulation of cellular protein localization | intracellular protein transport | positive regulation of cellular protein localization | neurotransmitter receptor transport | regulation of cell proliferation | cellular localization | secretion by cell | modulation of chemical synaptic transmission | regulation of cell adhesion | cell-cell signaling | regulation of neurotransmitter levels | synaptic vesicle cycle | system development | multicellular organism development | protein transport within lipid bilayer | regulation of protein localization to cell surface | synaptic vesicle fusion to presynaptic active zone membrane | localization within membrane | positive regulation of protein localization to plasma membrane | positive regulation of chemotaxis | positive regulation of protein localization to cell surface | protein localization to membrane | organic substance transport | synaptic signaling | peptide transport | cytokine-mediated signaling pathway | vesicle-mediated transport | cellular response to cytokine stimulus | establishment of vesicle localization | regulated exocytosis | receptor localization to synapse | protein localization to synapse | cell communication | positive regulation of protein localization to membrane | protein-containing complex localization | positive regulation of cell proliferation | regulation of locomotion | vesicle fusion | establishment of protein localization to membrane | neuron differentiation | response to organic substance | synaptic vesicle docking | plasma membrane fusion | anatomical structure development | cell surface receptor signaling pathway | cell projection organization | neurotransmitter receptor transport to postsynaptic membrane | regulation of protein localization to plasma membrane | cellular protein localization | amide transport | calcium ion regulated exocytosis | neuron projection development | vesicle docking | establishment of protein localization | vesicle organization | regulation of cell communication | signaling | cell development | synaptic vesicle localization | protein localization | cellular macromolecule localization | vesicle docking involved in exocytosis | establishment of protein localization to postsynaptic membrane | developmental process | organelle organization | neurotransmitter transport | signal release | regulation of synaptic plasticity | vesicle localization | long-term synaptic potentiation | synaptic vesicle transport | cellular response to organic substance | regulation of protein localization | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process

GO Cellular Component

presynaptic membrane | secretory granule | photoreceptor cell terminal bouton | zymogen granule | exocytic vesicle | integral component of membrane | dendrite | intracellular membrane-bounded organelle | synapse | apical plasma membrane | neuron projection | somatodendritic compartment | organelle membrane | cytoplasmic vesicle | cell | distal axon | intrinsic component of membrane | synaptic membrane | terminal bouton | lamellipodium | cytoplasm | intracellular organelle | dendritic tree | secretory granule membrane | apical part of cell | melanosome | presynapse | cell-cell junction | protein-containing complex | cell projection | secretory vesicle | endomembrane system | postsynapse | plasma membrane | cell leading edge | vacuole | vesicle | transport vesicle | extracellular exosome | specific granule | site of polarized growth | lytic vacuole | SNARE complex | synaptic vesicle | presynaptic active zone membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | vesicle membrane | axon terminus | zymogen granule membrane | presynaptic active zone | lysosome | extracellular space | cell periphery | axon | azurophil granule | growth cone | neuron projection terminus | ribbon synapse | intracellular vesicle | intracellular | cell junction | membrane | cytoplasmic vesicle membrane