QuickView for TAFI63 (gene)

Gene Symbol:

TAF1B Homo sapiens

Full name:

TATA-box binding protein associated factor, RNA polymerase I subunit B

Synonyms:

MGC:9349, RAF1B, RAFI63, SL1, TAFI63, TATA box-binding protein-associated factor RNA polymerase I subunit B, RNA polymerase I-specific TBP-associated factor 63 kDa, SL1, 63kD subunit, TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kD, TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa, TATA box-binding protein-associated factor 1B, TATA-box binding protein associated factor, RNA polymerase I, B, TBP-associated factor 1B, transcription initiation factor SL1/TIF-IB subunit B

Genomic Location:

Chr 2: 9901024-9991996

Description:

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory s...

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Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1-specific TAFs. Multiple transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

SCGGAAGY_ELK1_02

Cytogenetic Map:

2p25.1

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