QuickView for TALL2 (gene)

Gene Symbol:

TNFSF13 Homo sapiens

Full name:

TNF superfamily member 13

Synonyms:

APRIL, CD256, TALL-2, TALL2, TNLG7B, TRDL-1, UNQ383/PRO715, ZTNF2, tumor necrosis factor ligand superfamily member 13, TNF- and APOL-related leukocyte expressed ligand 2, a proliferation-inducing ligand, tumor necrosis factor (ligand) superfamily, member 13, tumor necrosis factor ligand 7B, tumor necrosis factor superfamily member 13, tumor necrosis factor-like protein ZTNF2, tumor necrosis factor-related death ligand-1

Genomic Location:

Chr 17: 7402340-7405642

Description:

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through ...

View Full Description

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E12_Q6 ,  PU1_Q6 ,  MYOD_01 ,  RYTTCCTG_ETS2_B ,  AML_Q6 ,  YTATTTTNR_MEF2_02 ,  STAT6_02 ,  E4BP4_01 ,  GCANCTGNY_MYOD_Q6 ,  TTAYRTAA_E4BP4_01 ,  GGGAGGRR_MAZ_Q6 ,  GGGYGTGNY_UNKNOWN ,  CAGGTG_E12_Q6 ,  E47_02 ,  CREBP1_01 ,  HLF_01 ,  CETS1P54_01 ,  RGAGGAARY_PU1_Q6 ,  ELF1_Q6 ,  LMO2COM_01 ,  OLF1_01

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-199

Cytogenetic Map:

17p13.1

search → result