QuickView for TALLA-1 (gene)

Gene Symbol:

TSPAN7 Homo sapiens

Full name:

tetraspanin 7

Synonyms:

A15, CCG-B7, CD231, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2, TM4SF2b, tetraspanin-7, CD231 antigen, T-cell acute lymphoblastic leukemia associated antigen 1, cell surface glycoprotein A15, membrane component chromosome X surface marker 1, membrane component, X chromosome, surface marker 1, tetraspanin protein, transmembrane 4 superfamily 2b, transmembrane 4 superfamily member 2, transmembrane protein A15, tspan-7

Genomic Location:

Chr X: 38305683-38433116

Description:

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation,...

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The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked cognitive disability and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CREBP1CJUN_01 ,  CREB_Q4_01 ,  AACTGAC_MIR223 ,  XBP1_01 ,  CTTTGA_LEF1_Q2 ,  TTAYRTAA_E4BP4_01 ,  CREB_Q4 ,  TGACCTY_ERR1_Q2 ,  GGGAGGRR_MAZ_Q6 ,  TGAYRTCA_ATF3_Q6 ,  ATF_B ,  CREBP1_Q2 ,  GTGACGY_E4F1_Q6 ,  RREB1_01 ,  ATF_01 ,  NKX62_Q2 ,  CREB_02 ,  ATF3_Q6 ,  CREBP1_01 ,  TGCCAAR_NF1_Q6 ,  AP2_Q3 ,  TGTTTGY_HNF3_Q6 ,  RORA1_01 ,  GFI1_01 ,  CEBP_Q3 ,  TAATTA_CHX10_01 ,  CEBP_C ,  AAAYRNCTG_UNKNOWN ,  CREB_Q2 ,  CP2_02 ,  CTGCAGY_UNKNOWN ,  TGACGTCA_ATF3_Q6 ,  RORA2_01 ,  CTGTTAC_MIR194 ,  ZF5_B ,  AACTTT_UNKNOWN ,  CREB_01 ,  TAXCREB_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-194 ,  Predicted Gene Targets for miR-223

Cytogenetic Map:

Xp11.4

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