QuickView for TAPK (gene)

Gene Symbol:

SCYL1 Homo sapiens

Full name:

SCY1 like pseudokinase 1

Synonyms:

GKLP, HT019, NKTL, NTKL, P105, SCAR21, TAPK, TEIF, TRAP, N-terminal kinase-like protein, SCY1-like protein 1, SCY1-like, kinase-like 1, coated vesicle-associated kinase of 90 kDa, likely ortholog of mouse N-terminal kinase-like protein, telomerase regulation-associated protein, telomerase transcriptional elements-interacting factor, teratoma-associated tyrosine kinase

Genomic Location:

Chr 11: 65049124-65062758

Description:

This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA poly...

View Full Description

This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

USF_Q6 ,  ATF6_01 ,  ARNT_01 ,  MYC_Q2 ,  MYCMAX_03 ,  CACGTG_MYC_Q2 ,  GGGCGGR_SP1_Q6 ,  HIF1_Q5 ,  USF_01 ,  NMYC_01 ,  SP1_Q6_01 ,  USF2_Q6 ,  HIF1_Q3

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-493-5p

Cytogenetic Map:

11q13.1

search → result