QuickView for TARS2 (gene)
- Gene Symbol:
- TARS2
Homo sapiens - Full name:
- threonyl-tRNA synthetase 2, mitochondrial
- Synonyms:
- COXPD21, TARSL1, thrRS, threonine--tRNA ligase, mitochondrial, threonyl-tRNA synthetase 2, mitochondrial (putative), threonyl-tRNA synthetase-like 1
- Genomic Location:
- Chr 1: 148726544-148746380
- Description:
-
This gene encodes a member of the class-II aminoacyl-tRNA synthetase family. The encoded protein is a mitochondrial aminoacyl-tRNA synthetase. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 4.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Canis lupus familiaris , Pan troglodytes , Gallus gallus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
1q21.2
| Transcripts Names |
|---|
| NM_025150 |
| NR_073513 |
| NM_001271896 |
| NR_073514 |
| NM_001271895 |
| XM_006711555 |
| XM_017002394 |
| XM_017002395 |
GO Molecular Function
ribonucleotide binding | carboxylic ester hydrolase activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | catalytic activity | aminoacyl-tRNA ligase activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | hydrolase activity, acting on ester bonds | identical protein binding | aminoacyl-tRNA editing activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | protein homodimerization activity | protein dimerization activity | ligase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | threonine-tRNA ligase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
RNA metabolic process | tRNA aminoacylation | cellular process | aminoacyl-tRNA metabolism involved in translational fidelity | cellular amino acid metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | peptide biosynthetic process | mitochondrial translation | cellular nitrogen compound biosynthetic process | threonyl-tRNA aminoacylation | cellular nitrogen compound metabolic process | cellular biosynthetic process | nitrogen compound metabolic process | small molecule metabolic process | cellular amide metabolic process | tRNA aminoacylation for protein translation | translation | tRNA aminoacylation for mitochondrial protein translation | biosynthetic process | aminoacyl-tRNA editing activity | peptide metabolic process | carboxylic acid metabolic process | tRNA metabolic process | mitochondrial threonyl-tRNA aminoacylation | protein metabolic process | metabolic process | mitochondrial gene expression | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | amide biosynthetic process | organic acid metabolic process | cellular protein metabolic process | cellular macromolecule biosynthetic process | regulation of translational fidelity | ncRNA metabolic process | heterocycle metabolic process | cellular metabolic process | mitochondrial RNA metabolic process | macromolecule metabolic process
GO Cellular Component
mitochondrial matrix | intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | membrane-enclosed lumen | intracellular
