QuickView for TAX1BP1 (gene)

Gene Symbol:

TAX1BP1 Homo sapiens

Full name:

Tax1 binding protein 1

Synonyms:

CALCOCO3, T6BP, TXBP151, tax1-binding protein 1, TRAF6-binding protein, Tax1 (human T-cell leukemia virus type I) binding protein 1

Genomic Location:

Chr 7: 27746263-27835911

Description:

This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammato...

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This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GTGACGY_E4F1_Q6 ,  GCGNNANTTCC_UNKNOWN ,  MGGAAGTG_GABP_B ,  SCGGAAGY_ELK1_02

Cytogenetic Map:

7p15.2

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