QuickView for TC21 (gene)

Gene Symbol:

RRAS2 Homo sapiens

Full name:

RAS related 2

Synonyms:

TC21, ras-related protein R-Ras2, ras-like protein TC21, related RAS viral (r-ras) oncogene homolog 2, teratocarcinoma oncogene

Genomic Location:

Chr 11: 14256042-14337305

Description:

This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of cer...

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This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

SMTTTTGT_UNKNOWN ,  AATGTGA_MIR23A_MIR23B ,  TAL1BETAITF2_01

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-323

Cytogenetic Map:

11p15.2

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