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QuickView for TCN1 (gene)


Gene Symbol:
TCN1 Homo sapiens Homo sapiens
Full name:
transcobalamin 1
Synonyms:
HC, TC-1, TC1, TCI, transcobalamin-1, haptocorin, haptocorrin, protein R, transcobalamin I (vitamin B12 binding protein, R binder family)
Genomic Location:
Chr 11: 59376857-59390617
Description:
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells.
Orthologs:
Macaca mulatta Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 11
11q12.1


Transcripts Names
NM_001062
Protein Names
Q8WV77
P20061
A8KAC5



GO Molecular Function

cofactor binding | vitamin binding | organic cyclic compound binding | tetrapyrrole binding | cobalamin binding | drug binding | heterocyclic compound binding | small molecule binding

GO Biological Process

exocytosis | neutrophil activation | cobalamin metabolic process | establishment of localization | response to drug | cellular process | secretion | leukocyte degranulation | localization | metal ion transport | transition metal ion transport | leukocyte activation | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | neutrophil degranulation | leukocyte activation involved in immune response | secretion by cell | cofactor metabolic process | nitrogen compound metabolic process | leukocyte mediated immunity | vitamin transport | organic substance transport | small molecule metabolic process | vesicle-mediated transport | regulated exocytosis | cobalt ion transport | cell activation involved in immune response | myeloid cell activation involved in immune response | neutrophil activation involved in immune response | drug metabolic process | vitamin metabolic process | cofactor transport | metabolic process | immune response | organic substance metabolic process | cell activation | drug transport | cobalamin transport | cation transport | neutrophil mediated immunity | heterocycle metabolic process | ion transport | immune system process | cellular metabolic process

GO Cellular Component

secretory granule | tertiary granule | cytoplasmic vesicle | cell | cytoplasmic vesicle lumen | cytoplasm | intracellular organelle | secretory vesicle | endomembrane system | vesicle | specific granule | extracellular region | membrane-bounded organelle | specific granule lumen | organelle | extracellular space | tertiary granule lumen | membrane-enclosed lumen | secretory granule lumen | intracellular vesicle | intracellular | vesicle lumen