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QuickView for TFF2 (gene)
- Gene Symbol:
- TFF2
Homo sapiens - Full name:
- trefoil factor 2
- Synonyms:
- SML1, SP, trefoil factor 2, spasmolysin, spasmolytic polypeptide, spasmolytic protein 1
- Genomic Location:
- Chr 21: 42639535-42644176
- Description:
-
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affec...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Canis lupus familiaris , Gallus gallus , Pan troglodytes , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
21q22.3
GO Molecular Function
signaling receptor binding | cytokine receptor binding | CXCR4 chemokine receptor binding | CXCR chemokine receptor binding | chemokine receptor binding | protein binding | G-protein coupled receptor binding
GO Biological Process
response to cytokine | chemokine-mediated signaling pathway | cellular process | regulation of cellular process | response to stimulus | cytokine-mediated signaling pathway | cellular response to cytokine stimulus | cell communication | response to organic substance | cell surface receptor signaling pathway | signaling | cellular response to organic substance | signal transduction
