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QuickView for THADA;jsessionid=16B6ABBB8606FDC78BA0BD54D92953E8 (gene)


Gene Symbol:
THADA Homo sapiens Homo sapiens
Full name:
THADA, armadillo repeat containing
Synonyms:
ARMC13, GITA, thyroid adenoma-associated protein, death receptor-interacting protein, gene inducing thyroid adenomas protein
Genomic Location:
Chr 2: 43311479-43676689
Description:
This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Canis lupus familiaris Gallus gallus Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 2
2p21





GO Molecular Function

protein binding

GO Biological Process

RNA metabolic process | RNA processing | regulation of localization | tRNA modification | cellular chemical homeostasis | adaptive thermogenesis | cellular process | cellular homeostasis | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | calcium ion homeostasis | RNA modification | RNA methylation | regulation of ATPase activity | ncRNA processing | negative regulation of transporter activity | cellular nitrogen compound metabolic process | negative regulation of transport | macromolecule modification | negative regulation of calcium ion transmembrane transport | negative regulation of transmembrane transport | metal ion homeostasis | nitrogen compound metabolic process | negative regulation of catalytic activity | regulation of catalytic activity | negative regulation of endoplasmic reticulum calcium ion concentration | methylation | cellular ion homeostasis | tRNA methylation | negative regulation of ion transmembrane transport | negative regulation of calcium ion transmembrane transporter activity | negative regulation of ion transport | negative regulation of calcium-transporting ATPase activity | regulation of calcium ion transmembrane transport | cation homeostasis | cellular cation homeostasis | negative regulation of calcium ion transport | cellular calcium ion homeostasis | homeostatic process | tRNA processing | tRNA metabolic process | negative regulation of ATPase activity | metabolic process | chemical homeostasis | nucleobase-containing compound metabolic process | negative regulation of ion transmembrane transporter activity | organic substance metabolic process | gene expression | ion homeostasis | regulation of ion transmembrane transport | negative regulation of molecular function | regulation of transmembrane transporter activity | regulation of ion transmembrane transporter activity | regulation of ion transport | endoplasmic reticulum calcium ion homeostasis | regulation of calcium ion transport | regulation of calcium-transporting ATPase activity | regulation of transport | ncRNA metabolic process | cellular metal ion homeostasis | heterocycle metabolic process | negative regulation of hydrolase activity | regulation of calcium ion transmembrane transporter activity | cellular metabolic process | divalent inorganic cation homeostasis | lipid homeostasis | macromolecule metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasmic side of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | cytoplasmic side of endoplasmic reticulum membrane | membrane-bounded organelle | organelle | cytosol | intracellular | membrane