QuickView for TIAM2 (gene)

Gene Symbol:

TIAM2 Homo sapiens

Full name:

T cell lymphoma invasion and metastasis 2

Synonyms:

STEF, TIAM-2, T-lymphoma invasion and metastasis-inducing protein 2, SIF and TIAM1-like exchange factor

Genomic Location:

Chr 6: 155453115-155620549

Description:

This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural...

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This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GGGCATT_MIR365

Cytogenetic Map:

6q25.2-q25.3

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