QuickView for TINT1 (gene)

Gene Symbol:

ACD Homo sapiens

Full name:

ACD, shelterin complex subunit and telomerase recruitment factor

Synonyms:

PIP1, PTOP, TINT1, TPP1, adrenocortical dysplasia protein homolog, POT1 and TIN2-interacting protein, TIN2 interacting protein 1, adrenocortical dysplasia homolog

Genomic Location:

Chr 16: 66248916-66252219

Description:

This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this comp...

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This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Gallus gallus

External Links:

Entrez Gene

Cytogenetic Map:

16q22.1

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