QuickView for TM2D3 (gene)

Gene Symbol:

TM2D3 Homo sapiens

Full name:

TM2 domain containing 3

Synonyms:

BLP2, TM2 domain-containing protein 3, BBP-like protein 2, almondex homolog, beta-amyloid-binding protein-like protein 2

Genomic Location:

Chr 15: 99999572-100010117

Description:

The protein encoded by this gene contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily. This protein has sequence and structural similarities to the beta-amyloid binding protein (BBP), but, unlike BBP, it does not regulate a response to beta-amyloid peptide. This protein may have regul...

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The protein encoded by this gene contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily. This protein has sequence and structural similarities to the beta-amyloid binding protein (BBP), but, unlike BBP, it does not regulate a response to beta-amyloid peptide. This protein may have regulatory roles in cell death or proliferation signal cascades. Several alternatively spliced transcript variants of this gene are described but the full length nature of some variants has not been determined. Multiple polyadenylation sites have been found in this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GABP_B ,  ATGTACA_MIR493 ,  AAAYRNCTG_UNKNOWN ,  NRF2_01 ,  MMEF2_Q6

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-493-5p

Cytogenetic Map:

15q26.3

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