QuickView for TNRC7 (gene)
- Gene Symbol:
- MED15
Homo sapiens - Full name:
- mediator complex subunit 15
- Synonyms:
- ARC105, CAG7A, CTG7A, PCQAP, TIG-1, TIG1, TNRC7, mediator of RNA polymerase II transcription subunit 15, CTG repeat protein 7a, PC2 (positive cofactor 2, multiprotein complex) glutamine/Q-rich-associated protein, PC2 glutamine/Q-rich-associated protein, PC2-glutamine-rich-associated protein, TPA inducible gene-1, TPA inducible protein, TPA-inducible gene 1 protein, activator-recruited cofactor 105 kDa component, activator-recruited cofactor, 105-kD, positive cofactor 2, glutamine/Q-rich-associated protein, trinucleotide repeat containing 7, trinucleotide repeat-containing gene 7 protein
- Genomic Location:
- Chr 22: 19191886-19271919
- Description:
-
The protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC/DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription. This gene contains stretches of trinucleotide repeats and is located in the chromosome 22 region which is deleted in DiGeorge syndrome. Alternative splicing results in mul...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
22q11.21
GO Molecular Function
protein binding | transcription coregulator activity
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | DNA-templated transcription, initiation | cellular process | stem cell population maintenance | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of gene expression | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | regulation of RNA metabolic process | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | maintenance of cell number | gene expression | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | developmental process | transcription coregulator activity | heterocycle metabolic process | cellular metabolic process | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | mediator complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular | membrane
