QuickView for TOB3 (gene)

Gene Symbol:

ATAD3B Homo sapiens

Full name:

ATPase family, AAA domain containing 3B

Synonyms:

AAA-TOB3, TOB3, ATPase family AAA domain-containing protein 3B, AAA-ATPase TOB3

Genomic Location:

Chr 1: 1397027-1421445

Description:

The protein encoded by this gene is localized to the mitochondrial inner membrane, where it can bind to a highly-related protein, ATAD3A. ATAD3A appears to interact with matrix nucleoid complexes, and the encoded protein negatively regulates that interaction. This gene is expressed almost exclusively in pluripotent embryonic stem cells and some can...

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The protein encoded by this gene is localized to the mitochondrial inner membrane, where it can bind to a highly-related protein, ATAD3A. ATAD3A appears to interact with matrix nucleoid complexes, and the encoded protein negatively regulates that interaction. This gene is expressed almost exclusively in pluripotent embryonic stem cells and some cancer cells. Two transcript variants encoding different isoforms have been found for this gene.

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External Links:

Entrez Gene

Transcription Factor
Binding Sites:

MYC_Q2 ,  CACGTG_MYC_Q2 ,  TGCGCANK_UNKNOWN ,  MYCMAX_01 ,  NMYC_01 ,  USF2_Q6

Cytogenetic Map:

1p36.33

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