QuickView for TOMM40;jsessionid=A77C08DA0E276B0F553678BB8BE4854F;jsessionid=6F27E75EAB661192DD7350011F9F28EC;jsessionid=C1BB27CCC67B6D0F6FA662EBDE9016B5;jsessionid=BB3531311C4E32BF481F0D14126342E2;jsessionid=D9BFEE1D8F69AA4C592179FF5C90203A (gene)
- Gene Symbol:
- TOMM40
Homo sapiens - Full name:
- translocase of outer mitochondrial membrane 40
- Synonyms:
- C19orf1, D19S1177E, PER-EC1, PEREC1, TOM40, mitochondrial import receptor subunit TOM40 homolog, mitochondrial outer membrane protein, p38.5, protein Haymaker, translocase of outer membrane 40 kDa subunit homolog, translocase of outer mitochondrial membrane 40 homolog
- Genomic Location:
- Chr 19: 50086334-50098783
- Description:
-
The protein encoded by this gene is localized in the outer membrane of the mitochondria. It is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for import of protein precursors into mitochondria. Alternatively spliced transcript variants have been found for this gene.
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
19q13.32
GO Molecular Function
protein transmembrane transporter activity | passive transmembrane transporter activity | transmembrane transporter activity | protein transporter activity | transporter activity | porin activity | protein binding | peptide transmembrane transporter activity | wide pore channel activity | channel activity
GO Biological Process
protein localization to mitochondrion | protein transmembrane transporter activity | establishment of localization | intracellular transport | cellular process | localization | protein transport | passive transmembrane transporter activity | protein transmembrane import into intracellular organelle | establishment of protein localization to mitochondrion | macromolecule localization | protein import into mitochondrial matrix | establishment of localization in cell | transmembrane transporter activity | cellular component organization | protein transporter activity | intracellular protein transport | cellular localization | mitochondrion organization | organic substance transport | mitochondrial transport | peptide transport | protein localization to organelle | porin activity | protein import | peptide transmembrane transporter activity | wide pore channel activity | establishment of protein localization to organelle | cellular protein localization | amide transport | mitochondrial transmembrane transport | establishment of protein localization | transmembrane transport | intracellular protein transmembrane transport | protein localization | cellular macromolecule localization | channel activity | protein targeting to mitochondrion | organelle organization | protein transmembrane transport | protein targeting | ion transport
GO Cellular Component
integral component of organelle membrane | integral component of membrane | organelle inner membrane | intracellular membrane-bounded organelle | mitochondrial inner membrane | organelle membrane | cell | organelle outer membrane | intrinsic component of membrane | cytoplasm | outer mitochondrial membrane protein complex | intracellular organelle | protein-containing complex | mitochondrion | mitochondrial outer membrane translocase complex | intrinsic component of mitochondrial outer membrane | membrane-bounded organelle | organelle | mitochondrial outer membrane | mitochondrial envelope | pore complex | outer membrane | integral component of mitochondrial membrane | mitochondrial membrane | cytosol | intracellular | integral component of mitochondrial outer membrane | membrane
